[HTML][HTML] Non-alcoholic fatty liver disease and diabetes: from physiopathological interplay to diagnosis and treatment

NC Leite, CA Villela-Nogueira… - World journal of …, 2014 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) is highly prevalent in patients with diabetes
mellitus and increasing evidence suggests that patients with type 2 diabetes are at a …

Insulin therapy in people with type 2 diabetes: opportunities and challenges?

P Home, M Riddle, WT Cefalu, CJ Bailey… - Diabetes …, 2014 - Am Diabetes Assoc
Given the continued interest in defining the optimal management of individuals with type 2
diabetes, the Editor of Diabetes Care convened a working party of diabetes specialists to …

Coinfusion of low-dose GLP-1 and glucagon in man results in a reduction in food intake

J Cegla, RC Troke, B Jones, G Tharakan, J Kenkre… - Diabetes, 2014 - Am Diabetes Assoc
Obesity is a growing epidemic, and current medical therapies have proven inadequate.
Endogenous satiety hormones provide an attractive target for the development of drugs that …

Obesity and liver disease: the epidemic of the twenty-first century

KE Corey, LM Kaplan - Clinics in liver disease, 2014 - liver.theclinics.com
Obesity, defined as the state of having excess body fat, is an epidemic and stillgrowing
health problem across the world. Data from the 2009–2010 National Health and Nutrition …

Prevención, diagnóstico y tratamiento de la obesidad. Posicionamiento de la Sociedad Española para el Estudio de la Obesidad de 2016

A Lecube, S Monereo, MÁ Rubio… - … . diabetes nutr.(Ed …, 2017 - pesquisa.bvsalud.org
Prevención, diagnóstico y tratamiento de la obesidad. Posicionamiento de la Sociedad
Española para el Estudio de la Obesidad de 2016 | Endocrinol. diabetes nutr. (Ed. impr.);64(supl.1) …

Short‐term effects of liraglutide on kidney function and vasoactive hormones in type 2 diabetes: a randomized clinical trial

J Skov, M Pedersen, JJ Holst, B Madsen… - Diabetes, Obesity …, 2016 - Wiley Online Library
Aims To investigate the effects of a single dose of 1.2 mg liraglutide, a once‐daily glucagon‐
like peptide‐1 (GLP‐1) receptor agonist, on key renal variables in patients with type 2 …

[HTML][HTML] Novel strategies for glycaemic control and preventing diabetic complications applying the clustering-based classification of adult-onset diabetes mellitus: a …

H Tanabe, H Masuzaki, M Shimabukuro - Diabetes research and clinical …, 2021 - Elsevier
Diabetes mellitus results from an interplay between insulin resistance and β-cell dysfunction.
Since their relative contributions to its pathogenesis are difficult to quantify, therapeutic …

Emerging combinatorial hormone therapies for the treatment of obesity and T2DM

SA Sadry, DJ Drucker - Nature Reviews Endocrinology, 2013 - nature.com
Peptide hormones and proteins control body weight and glucose homeostasis by engaging
peripheral and central metabolic signalling pathways responsible for the maintenance of …

Gut-pancreas-liver axis as a target for treatment of NAFLD/NASH

G Svegliati-Baroni, B Patrício, G Lioci… - International journal of …, 2020 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) represents the most common form of chronic liver
disease worldwide. Due to its association with obesity and diabetes and the fall in hepatitis …

The extra‐pancreatic effects of GLP‐1 receptor agonists: a focus on the cardiovascular, gastrointestinal and central nervous systems

J Seufert, B Gallwitz - Diabetes, Obesity and Metabolism, 2014 - Wiley Online Library
The glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) exenatide, liraglutide and
lixisenatide have been shown to improve glycaemic control and beta‐cell function with a low …