Biological Assay-Guided Fractionation and Mass Spectrometry-Based Metabolite Profiling of Annona muricata L. Cytotoxic Compounds against Lung Cancer A549 …

ELO Salac, MR Alvarez, RS Gaurana, SJB Grijaldo… - Plants, 2022 - mdpi.com
Annona muricata L.(Guyabano) leaves are reported to exhibit anticancer activity against
cancer cells. In this study, the ethyl acetate extract from guyabano leaves was purified …

Michael Acceptors as Anti-Cancer Compounds: Coincidence or Causality?

CMC Andrés, JM Pérez de la Lastra… - International Journal of …, 2024 - mdpi.com
Michael acceptors represent a class of compounds with potential anti-cancer properties.
They act by binding to nucleophilic sites in biological molecules, thereby disrupting cancer …

Integrating Computational Methods in Network Pharmacology and In Silico Screening to Uncover Multi-targeting Phytochemicals against Aberrant Protein …

SJB Grijaldo, MRS Alvarez, FM Heralde III… - ACS …, 2023 - ACS Publications
Glycoproteins are an underexploited drug target for cancer therapeutics. In this work, we
integrated computational methods in network pharmacology and in silico docking …

Antitumor Potential of Annona muricata Linn. An Edible and Medicinal Plant in Mexico: In Vitro, In Vivo, and Toxicological Studies

V Merlín-Lucas, RM Ordoñez-Razo, F Calzada, A Solís… - Molecules, 2021 - mdpi.com
Annona muricata (Am) is a plant used in traditional Mexican medicine to treat cancer. In this
study, ethanol extracts of Am collected in Acapulco and Tecpan from Guerrero state were …

Alkaloids and terpenoids: synthesis, classification, isolation and purification, reactions, and applications

MM Phukan, SR Sangma, D Kalita, P Bora… - Handbook of …, 2023 - Elsevier
In the past few decades there has been a tremendous spike in studies pertaining to
secondary metabolite research specifically with regard to their prominence as a source of …

Bio-fabrication and efficiency analysis of Annona muricata extract coated on bamboo fiber for wound healing application

Y RT, P VS, SK, B Jayaprakash - Journal of Natural Fibers, 2023 - Taylor & Francis
This study focusses on the bio-fabrication of leaf extracts of Annona muricata dyed bamboo
woven fabric and its application in wound healing. Annona muricata was exposed to …

[PDF][PDF] Molecular docking of secondary metabolites from Indonesian marine and terrestrial organisms targeting SARS-CoV-2 ACE-2, M pro, and PL pro receptors

G Syahputra, N Gustini, B Bustanussalam… - …, 2021 - pharmacia.pensoft.net
With the uncontrolled spread of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2), development and distribution of antiviral drugs and vaccines have gained …

Evaluation of Annona muricata (Graviola) leaves activity against experimental trichinellosis: In vitro and in vivo studies

ES El-Wakil, HF Abdelmaksoud… - Journal of …, 2021 - cambridge.org
Our work aimed to evaluate the possible effect of Annona muricata (Graviola) leaf extract on
Trichinella spiralis in in vitro and in vivo studies. Trichinella spiralis worms were isolated …

[PDF][PDF] Molecular Docking and physicochemical analysis of the active compounds of Soursop (Annonamuricata Linn) for an anti-breast cancer agent

T Sumaryada, AS Astarina… - Biointerface Res. Appl …, 2021 - academia.edu
Breast cancer cases continue to increase every year. One plant that potentially has the
antibreast-cancer activity is soursop. Some compounds in soursop (Annona muricata Linn) …

[HTML][HTML] An in silico study of bioactive compounds of Annona muricata in the design of ani-prostate cancer agent: MM/GBSA, pharmacophore modeling and ADMET …

VO Apeh, AE Adegboyega, IF Chukwuma… - Informatics in Medicine …, 2023 - Elsevier
One of the most frequent diseases that affect and kill men globally is prostate cancer.
Treatment for prostate cancer has become unpleasant and upsetting for individuals due to …