This “year in review” provides a summary of the research findings on the topic of genetics,
genomics and epigenetics for osteoarthritis (OA) between Mar 2021–Apr 2022. A search …

Osteoarthritis (OA) is one of the most common refractory degenerative joint diseases
worldwide. Synovitis is believed to drive joint cartilage destruction during OA pathogenesis …

Background Osteoarthritis (OA) is a common chronic joint disease, but the association
between molecular and cellular events and the pathogenic process of OA remains unclear …

Background Recurrent pregnancy loss defined as the occurrence of two or more pregnancy
losses before 20-24 weeks of gestation, is a prevalent and significant pathological condition …

Background Autophagy plays a critical role in the progression of osteoarthritis (OA), mainly
by regulating inflammatory and immune responses. However, the underlying mechanisms …

Osteosarcoma is a highly metastatic malignant bone tumor, necessitating the development
of new treatments to target its metastasis. Recent studies have revealed the significance of …

Background Idiopathic pulmonary fibrosis (IPF) is a progressive chronic interstitial lung
disease with limited therapeutic options. Cuproptosis is a recently proposed novel form of …

Tubulointerstitial fibrosis is an important pathological feature of diabetic nephropathy that is
associated with impaired renal function. However, the mechanism by which fibrosis occurs …

Osteoarthritis (OA) is a major cause of pain, disability, and social burden in the elderly
throughout the world. Although many studies focused on the molecular mechanism of OA, its …

Osteoarthritis (OA) is a prevalent joint disease globally. TNFA is recognized as a crucial
inflammatory cytokine that plays a significant role in the pathophysiological mechanisms that …