Malaria is a leading cause of mortality and morbidity globally, and effective vaccines are
urgently needed. Malaria vaccine approaches can be broadly grouped as pre‐erythrocytic …

In areas where Plasmodium falciparum transmission is endemic, clinical immunity against
malaria is progressively acquired during childhood and adults are usually protected against …

Cytoadherance of Plasmodium falciparum-infected erythrocytes in the brain, organs and
peripheral microvasculature is linked to morbidity and mortality associated with severe …

Discovering novel genes involved in immune evasion and drug resistance in the human
malaria parasite, Plasmodium falciparum, is of critical importance to global health. Such …

Malaria during pregnancy causes serious disease that is associated with sequestration in
the placenta of Plasmodium falciparum infected erythrocytes that adhere to several host …

VAR2CSA is the main candidate for a pregnancy malaria vaccine, but vaccine development
may be complicated by sequence polymorphism. Here, we obtained partial or full-length …

Women in endemic areas become highly susceptible to malaria during first and second
pregnancies, despite immunity acquired after years of exposure. Recent insights have …

Determining the diversity of PfEMP1 sequences expressed by Plasmodium falciparum-
infected erythrocytes isolated from placentas is important for attempts to develop a …

Until recently, malaria vaccine development efforts have focused almost exclusively on a
handful of well characterized Plasmodium falciparum antigens. Despite dedicated work by …

The malaria parasite Plasmodium falciparum traffics the virulence protein P. falciparum
erythrocyte membrane protein 1 (Pf EMP1) to the surface of infected red blood cells (RBCs) …