[HTML][HTML] The time course and mechanisms of change in biomarkers of joint metabolism in response to acute exercise and chronic training in physiologic and …

HM Roberts, RJ Law, JM Thom - European Journal of Applied Physiology, 2019 - Springer
Purpose The benefits of exercise across the lifespan and for a wide spectrum of health and
diseases are well known. However, there remains less clarity as to the effects of both acute …

Suramin ameliorates osteoarthritis by acting on the Nrf2/HO-1 and NF-κB signaling pathways in chondrocytes and promoting M2 polarization in macrophages

P Shen, SH Huang, ZM Liu, CC Lu, SH Chou… - International …, 2023 - Elsevier
Osteoarthritis (OA)—the most prevalent of arthritis diseases—is a complicated pathogenesis
caused by cartilage degeneration and synovial inflammation. Suramin has been reported to …

[HTML][HTML] Small noncoding RNAs in knee osteoarthritis: the role of MicroRNAs and tRNA-derived fragments

J Zacharjasz, AM Mleczko, P Bąkowski… - International journal of …, 2021 - mdpi.com
Knee osteoarthritis (OA) is a degenerative knee joint disease that results from the
breakdown of joint cartilage and underlying bone, affecting about 3.3% of the world's …

[HTML][HTML] Clinical-like cryotherapy improves footprint patterns and reduces synovial inflammation in a rat model of post-traumatic knee osteoarthritis

GM Barbosa, JE Cunha, TM Cunha, LB Martinho… - Scientific Reports, 2019 - nature.com
Cryotherapy is a non-pharmacological treatment commonly used to control inflammation
and improve function after acute traumas. However, there are no definitive findings about its …

[HTML][HTML] Investigation of cytokine changes in osteoarthritic knee joint tissues in response to hyperacute serum treatment

D Kardos, B Marschall, M Simon, I Hornyák… - Cells, 2019 - mdpi.com
One option to fight joint degradation and inflammation in osteoarthritis is the injection of
activated blood products into the synovial space. It has been demonstrated that hyperacute …

[HTML][HTML] Methods of Conservative Intra-Articular Treatment for Osteoarthritis of the Hip and Knee

R Ossendorff, D Thimm, DC Wirtz… - Deutsches Ärzteblatt …, 2023 - ncbi.nlm.nih.gov
Background Osteoarthritis is a degenerative joint disease that is becoming increasingly
common as the population ages. Conservative treatment for hip or knee osteoarthritis has …

[HTML][HTML] Rhein laden pH-responsive polymeric nanoparticles for treatment of osteoarthritis

B Hu, F Gao, C Li, B Zhang, M An, M Lu, Y Liu, Y Liu - AMB Express, 2020 - Springer
Osteoarthritis (OA) is a condition associated with severe inflammation, cartilage destruction
and degeneration of joints. Rhein (Rh) is an effective anti-inflammatory drug with proven …

[HTML][HTML] Modulation of inflammatory mediators by polymeric nanoparticles loaded with anti-inflammatory drugs

GM Pontes-Quero, L Benito-Garzón, J Pérez Cano… - Pharmaceutics, 2021 - mdpi.com
The first-line treatment of osteoarthritis is based on anti-inflammatory drugs, the most
currently used being nonsteroidal anti-inflammatory drugs, selective cyclooxygenase 2 …

[PDF][PDF] Systemic blood plasma CCL5 and CXCL6: potential biomarkers for human lumbar disc degeneration

S Grad, C Bow, J Karppinen, KD Luk, KM Cheung… - Eur Cell …, 2016 - researchgate.net
Lumbar disc degeneration severity on magnetic resonance imaging (MRI) is associated with
low back pain. Proinflammatory chemokines CCL5 and CXCL6 are released by induced …

A preliminary study of combined detection of COMP, TIMP-1, and MMP-3 in synovial fluid: potential indicators of osteoarthritis progression

J Plsikova Matejova, T Spakova, D Harvanova… - Cartilage, 2021 - journals.sagepub.com
Objective Osteoarthritis (OA) commonly affects weight-bearing joints and is characterized by
articular cartilage breakdown combined with osteophyte formation at the joint margins and …