Antigenicity and receptor affinity of SARS-CoV-2 BA. 2.86 spike

Q Wang, Y Guo, L Liu, LT Schwanz, Z Li, MS Nair, J Ho… - Nature, 2023 - nature.com
A severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariant, BA.
2.86, has emerged and spread to numerous countries worldwide, raising alarm because its …

[HTML][HTML] Fast evolution of SARS-CoV-2 BA. 2.86 to JN. 1 under heavy immune pressure

S Yang, Y Yu, Y Xu, F Jian, W Song… - The Lancet Infectious …, 2024 - thelancet.com
The SARS-CoV-2 saltation variant BA. 2.86, which was quickly designated as a variant
under monitoring after its emergence, has garnered global attention. Although BA. 2.86 did …

[HTML][HTML] Evolution and neutralization escape of the SARS-CoV-2 BA. 2.86 subvariant

K Khan, G Lustig, C Römer, K Reedoy, Z Jule… - Nature …, 2023 - nature.com
Abstract Omicron BA. 2.86 subvariant differs from Omicron BA. 2 as well as recently
circulating variants by over 30 mutations in the spike protein alone. Here we report on the …

[HTML][HTML] Distinct evolution of SARS-CoV-2 Omicron XBB and BA. 2.86/JN. 1 lineages combining increased fitness and antibody evasion

D Planas, I Staropoli, V Michel, F Lemoine… - Nature …, 2024 - nature.com
The unceasing circulation of SARS-CoV-2 leads to the continuous emergence of novel viral
sublineages. Here, we isolate and characterize XBB. 1, XBB. 1.5, XBB. 1.9. 1, XBB. 1.16. 1 …

Virological characteristics of the SARS-CoV-2 JN. 1 variant

Y Kaku, K Okumura, M Padilla-Blanco… - The Lancet Infectious …, 2024 - thelancet.com
4 Yang S, Yu Y, Jian F, et al. Antigenicity and infectivity characterisation of SARS-CoV-2 BA.
2.86. Lancet Infect Dis 2023; 23: e457–59. 5 Kosugi Y, Plianchaisuk A, Putri O, et al …

[HTML][HTML] Humoral immune escape by current SARS-CoV-2 variants BA. 2.86 and JN. 1, December 2023

LM Jeworowski, B Mühlemann, F Walper… - …, 2024 - eurosurveillance.org
Variant BA. 2.86 and its descendant, JN. 1, of SARS-CoV-2 are rising in incidence across
Europe and globally. We isolated recent JN. 1, BA. 2.86, EG. 5, XBB. 1.5 and earlier variants …

[HTML][HTML] Virological characteristics of the SARS-CoV-2 BA. 2.86 variant

T Tamura, K Mizuma, H Nasser, S Deguchi… - Cell Host & Microbe, 2024 - cell.com
In late 2023, several SARS-CoV-2 XBB descendants, notably EG. 5.1, were predominant
worldwide. However, a distinct SARS-CoV-2 lineage, the BA. 2.86 variant, also emerged …

[HTML][HTML] Immune evasion, infectivity, and fusogenicity of SARS-CoV-2 BA. 2.86 and FLip variants

P Qu, K Xu, JN Faraone, N Goodarzi, YM Zheng… - Cell, 2024 - cell.com
Evolution of SARS-CoV-2 requires the reassessment of current vaccine measures. Here, we
characterized BA. 2.86 and XBB-derived variant FLip by investigating their neutralization …

[HTML][HTML] Deep mutational scans of XBB. 1.5 and BQ. 1.1 reveal ongoing epistatic drift during SARS-CoV-2 evolution

AL Taylor, TN Starr - PLoS Pathogens, 2023 - journals.plos.org
Substitutions that fix between SARS-CoV-2 variants can transform the mutational landscape
of future evolution via epistasis. For example, large epistatic shifts in mutational effects …

SARS-CoV-2 BA. 2.86 enters lung cells and evades neutralizing antibodies with high efficiency

L Zhang, A Kempf, I Nehlmeier, A Cossmann, A Richter… - Cell, 2024 - cell.com
Summary BA. 2.86, a recently identified descendant of the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) Omicron BA. 2 sublineage, contains∼ 35 mutations …