Over recent years, many researchers have supported the autoimmune theory of sarcoidosis.
The presence of uncontrolled inflammatory response on local and system levels in patients …

The differentiation of naive CD8+ T cells into effector cells is important for establishing
immunity. However, the effect of heterogeneous naive CD8+ T cell populations is not fully …

Background Breast cancer (BC) is the most common malignancy among women in the
world. Alternative splicing (AS) is an important mechanism for regulating gene expression …

Simple Summary Chronic obstructive pulmonary disease (COPD) is a risk factor for lung
cancer independent of the influence of tobacco smoke. There are some similarities in …

Hepatology Publish Ahead of Print DOI:10.1097/HEP.0000000000000830 Page 1 Antagonistic
effects of the cytotoxic molecules granzyme B and TRAIL in the immunopathogenesis of …

Infection with Leishmania amazonensis and L. mexicana may lead to diffuse cutaneous
leishmaniasis. The cure is exceptional, especially for the strange case of this lady. Case …

E and inhibitor of DNA binding (ID) proteins are involved in various cellular developmental
processes and effector activities in T cells. Recent findings indicate that E and ID proteins …

Infection with Trypanosoma cruzi remains the most important neglected zoonosis in Latin
America. This infection does not lead to specific symptoms in the acute phase, but chronic …

Abstract Distinct Natural Killer (NK)-like CD57+ and PD-1+ CD8+ exhausted-like T cell
populations (Tex) have both been linked to beneficial immunotherapy response in …

Simple Summary Immune-cell activation is triggered upon antigen or target recognition. This
is modulated by co-stimulatory or co-inhibitory signals provided by the cellular environment …