Integrin α4β7+ T cells perpetuate tissue injury in chronic inflammatory diseases, yet their
role in hepatic fibrosis progression remains poorly understood. Here, we report increased …

Adoptive cell therapy has revolutionized cancer treatment, especially for hematologic
malignancies. T cells are the most extensively utilized cells in adoptive cell therapy …

Previous studies in Uncaria tomentosa have shown promising results concerning the
characterization of polyphenols with leaves yielding more diverse proanthocyanidins and …

Introduction Alveolar epithelial regeneration depends on the activity of resident quiescent
progenitor cells. Alveolar epithelial type II (AT2) cells are known as the alveolar epithelial …

We previously found that kidney-infiltrating T cells (KITs) in murine lupus nephritis (LN)
resembled dysfunctional T cells that infiltrate tumors. This unexpected finding raised the …

Autoimmune encephalitis (AIE) is a type of immunoreactive encephalitic disorder and is
recognized as the most prevalent noninfectious encephalitis. Nevertheless, the rarity of …

Common variable immunodeficiency (CVID) is an inborn error of immunity characterized by
low levels of antibodies. In addition to infections, many patients also suffer from T-helper 1 …

Purpose Hepatocellular carcinoma has become one of the severe diseases threatening
human health. T cell exhaustion is deemed as a reason for immunotherapy resistance …

Simple Summary Despite the high prevalence of cutaneous squamous cell carcinoma
(cSCC), one of the most frequent human cancers, the tumor microenvironment (TME) of this …

Chronic, nonhealing wounds remain a clinical challenge and a significant burden for the
healthcare system. Skin-resident and infiltrating T cells that recognize pathogens …