[HTML][HTML] Immune Cell-Mediated Autoimmune Responses in Severe Asthma
Severe asthma (SA) has heterogeneous inflammatory phenotypes characterized by
persistent airway inflammation (eosinophilic and/or neutrophilic inflammation) and …
persistent airway inflammation (eosinophilic and/or neutrophilic inflammation) and …
[HTML][HTML] Identification of MICALL2 as a novel prognostic biomarker correlating with inflammation and T cell exhaustion of kidney renal clear cell carcinoma
W Lin, W Chen, J Zhong, H Ueki, A Xu… - Journal of …, 2022 - ncbi.nlm.nih.gov
Purpose: The interplay of inflammation and immunity affects all stages from tumorigenesis to
progression, and even tumor response to therapy. A growing interest has been attracted …
progression, and even tumor response to therapy. A growing interest has been attracted …
CD7 activation regulates cytotoxicity-driven pathology in systemic sclerosis, yielding a target for selective cell depletion
TI Papadimitriou, P Singh, A van Caam… - Annals of the …, 2024 - ard.bmj.com
Objectives Cytotoxic T cells and natural killer (NK) cells are central effector cells in cancer
and infections. Their effector response is regulated by activating and inhibitory receptors …
and infections. Their effector response is regulated by activating and inhibitory receptors …
Epigenetic and metabolic regulation of immunity during infection or cancer and associated immune biomarkers
V Barili, P Fisicaro, C Boni - Frontiers in Immunology, 2023 - frontiersin.org
The intricate interplay between epigenetic modifications, metabolic processes, and immune
responses has garnered significant awareness in the context of infections and cancer (1, 2) …
responses has garnered significant awareness in the context of infections and cancer (1, 2) …
Amniotic MSC affect CD8 naive polarization toward SLEC/MPEC subsets by down-modulating IL-12Rβ1 and IL-2Rα signaling pathways
A Papait, E Vertua, PB Signoroni, A Cargnoni… - Iscience, 2023 - cell.com
Mesenchymal stromal cells (MSCs) are known for their immunomodulatory activity. Here, we
report that MSCs isolated from the amniotic membrane of human term placenta (hAMSCs) …
report that MSCs isolated from the amniotic membrane of human term placenta (hAMSCs) …
[HTML][HTML] Unraveling the Immune Microenvironment in Diffuse Large B-Cell Lymphoma: Prognostic and Potential Therapeutic Implications
E Koumpis, A Papoudou-Bai, K Papathanasiou… - Current Issues in …, 2024 - mdpi.com
Diffuse large B cell lymphoma (DLBCL) is a multifaceted condition characterized by
significant diversity in its molecular and pathological subtypes and clinical manifestation …
significant diversity in its molecular and pathological subtypes and clinical manifestation …
A Lower Dose of Infection Generates a Better Long-Term Immune Response against Toxoplasma gondii
MM Moretto, J Chen, M Meador, J Phan, IA Khan - ImmunoHorizons, 2023 - journals.aai.org
Toxoplasma gondii, an obligate intracellular pathogen, induces a strong immune response
in the infected host. In the encephalitis model of infection, long-term protective immunity is …
in the infected host. In the encephalitis model of infection, long-term protective immunity is …
Revolutionizing tumor immunotherapy: unleashing the power of progenitor exhausted T cells
Z Fang, X Ding, H Huang, H Jiang… - Cancer Biology & …, 2024 - cancerbiomed.org
In exploring persistent infections and malignancies, a distinctive subgroup of CD8+ T cells,
progenitor exhausted CD8+ T (Tpex) cells, has been identified. These Tpex cells are notable …
progenitor exhausted CD8+ T (Tpex) cells, has been identified. These Tpex cells are notable …
Deconvolution of bulk gene expression profiles reveals the association between immune cell polarization and the prognosis of hepatocellular carcinoma patients
YJ Chiu, CE Ni, YH Huang - Cancer Medicine, 2023 - Wiley Online Library
Background Many studies have utilized computational methods, including cell composition
deconvolution (CCD), to correlate immune cell polarizations with the survival of cancer …
deconvolution (CCD), to correlate immune cell polarizations with the survival of cancer …
HArmonized single-cell RNA-seq Cell type Assisted Deconvolution (HASCAD)
YJ Chiu, CE Ni, YH Huang - BMC Medical Genomics, 2023 - Springer
Background Cell composition deconvolution (CCD) is a type of bioinformatic task to estimate
the cell fractions from bulk gene expression profiles, such as RNA-seq. Many CCD models …
the cell fractions from bulk gene expression profiles, such as RNA-seq. Many CCD models …