[HTML][HTML] GDF15 and cardiac cells: current concepts and new insights
L Rochette, G Dogon, M Zeller, Y Cottin… - International journal of …, 2021 - mdpi.com
Growth and differentiation factor 15 (GDF15) belongs to the transforming growth factor-β
(TGF-β) superfamily of proteins. Glial-derived neurotrophic factor (GDNF) family receptor α …
(TGF-β) superfamily of proteins. Glial-derived neurotrophic factor (GDNF) family receptor α …
[HTML][HTML] Insights into mechanisms of GDF15 and receptor GFRAL: therapeutic targets
L Rochette, M Zeller, Y Cottin, C Vergely - Trends in Endocrinology & …, 2020 - cell.com
Growth and differentiation factor 15 (GDF15) belongs to the transforming growth factor-β
(TGF-β) superfamily proteins. GDF15 acts as an inflammatory marker, and it plays a role in …
(TGF-β) superfamily proteins. GDF15 acts as an inflammatory marker, and it plays a role in …
The multiple facets of the TGF-β family cytokine growth/differentiation factor-15/macrophage inhibitory cytokine-1
K Unsicker, B Spittau, K Krieglstein - Cytokine & growth factor reviews, 2013 - Elsevier
Abstract GDF-15 (also MIC-1, NAG-1, PLAB, PTGFB) is a member of the TGF-β superfamily,
which is widely distributed in mammalian tissues and has been shown to play multiple roles …
which is widely distributed in mammalian tissues and has been shown to play multiple roles …
[HTML][HTML] Novel insights into astrocyte-mediated signaling of proliferation, invasion and tumor immune microenvironment in glioblastoma
Glioblastoma (GBM) continues to be the most aggressive cancer of the brain. The dismal
prognosis is largely attributed to the microenvironment surrounding tumor cells. Astrocytes …
prognosis is largely attributed to the microenvironment surrounding tumor cells. Astrocytes …
Roles of growth differentiation factor 15 in atherosclerosis and coronary artery disease
J Wang, L Wei, X Yang, J Zhong - Journal of the American Heart …, 2019 - Am Heart Assoc
The majority of acute cardiovascular events (CVE) in patients are caused by occlusive
thrombosis because of rupture or erosion of atherosclerotic plaques. 1 Growth differentiation …
thrombosis because of rupture or erosion of atherosclerotic plaques. 1 Growth differentiation …
[HTML][HTML] GDF15 as a key disease target and biomarker: Linking chronic lung diseases and ageing
Y Wan, J Fu - Molecular and cellular biochemistry, 2024 - Springer
Abstract Growth differentiation factor 15 (GDF15), a member of the transforming growth
factor-beta superfamily, is expressed in several human organs. In particular, it is highly …
factor-beta superfamily, is expressed in several human organs. In particular, it is highly …
[HTML][HTML] GDF15 secreted by senescent endothelial cells improves vascular progenitor cell functions
G Ha, F De Torres, N Arouche, N Benzoubir… - PLoS …, 2019 - journals.plos.org
Endothelial dysfunction (ED) is part of the first steps in the development of cardiovascular
diseases (CVD). Growth Differentiation Factor 15 (GDF15) is a cytokine belonging to the …
diseases (CVD). Growth Differentiation Factor 15 (GDF15) is a cytokine belonging to the …
[HTML][HTML] Role of growth differentiation factor 15 in lung disease and senescence: potential role across the lifespan
F Al-Mudares, S Reddick, J Ren, A Venkatesh… - Frontiers in …, 2020 - frontiersin.org
Growth Differentiation Factor 15 (GDF15) is a divergent member of transforming growth
factor-beta (TGF-β) superfamily and is ubiquitously expressed, under normal physiological …
factor-beta (TGF-β) superfamily and is ubiquitously expressed, under normal physiological …
Loss of growth differentiation factor 15 exacerbates lung injury in neonatal mice
F Al-Mudares, M Cantu Gutierrez… - … of Physiology-Lung …, 2023 - journals.physiology.org
Growth differentiation factor 15 (GDF15) is a divergent member of the transforming growth
factor-β (TGF-β) superfamily, and its expression increases under various stress conditions …
factor-β (TGF-β) superfamily, and its expression increases under various stress conditions …
[HTML][HTML] Emerging roles of growth differentiation factor‑15 in brain disorders
WW Jiang, ZZ Zhang, PP He… - Experimental and …, 2021 - spandidos-publications.com
Brain disorders, such as Alzheimer's and Parkinson's disease and cerebral stroke, are an
important contributor to mortality and disability worldwide, where their pathogenesis is …
important contributor to mortality and disability worldwide, where their pathogenesis is …