Mitochondrial impairment has been associated with the development of insulin resistance,
the hallmark of type 2 diabetes mellitus (T2DM). However, the relationship between …

Theragnostics is a promising approach that integrates diagnostics and therapeutics into a
single personalized strategy. To conduct effective theragnostic studies, it is essential to …

Linked to exacerbated inflammation, myocarditis is a cardiovascular disease, which may
lead to dilated cardiomyopathy. Although sex and age differences in the development of …

The prevailing notion that reduced cofactors NADH and FADH 2 transfer electrons from the
tricarboxylic acid cycle to the mitochondrial electron transfer system creates ambiguities …

In cardiology, acetylsalicylic acid (ASA) and warfarin are among the most commonly used
prophylactic therapies against thromboembolic events. Drug–drug interactions are generally …

The excessive intracellular Ca 2+ can induce oxidative stress, mitochondrial damage and
cell apoptosis, which has been extensively explored for tumor therapy. However, the low Ca …

3-nitropropionic acid (3-NP) is a potent mitochondrial inhibitor mycotoxin. Systemic
administration of 3-NP can induce Huntington's disease (HD)-like symptoms in experimental …

Essential oils sourced from herbs commonly used in the Mediterranean diet have
demonstrated advantageous attributes as nutraceuticals and prebiotics within a model of …

Mitochondrial dysfunction and the activation of multiple programmed cell death (PCD) have
been shown to aggravate the severity and mortality associated with the progression of …

Late cardiotoxicity is a formidable challenge in anthracycline-based anticancer treatments.
Previous research hypothesized that co-administration of carvedilol (CVD) and dexrazoxane …