Cerebral small vessel disease (SVD) causes lacunar stroke and intracerebral hemorrhage,
and is the most common pathology underlying vascular cognitive impairment. Increasingly …

Immune memory is a defining feature of the acquired immune system, but activation of the
innate immune system can also result in enhanced responsiveness to subsequent triggers …

Vascular cognitive impairment and dementia (VCID) is commonly caused by vascular
injuries in cerebral large and small vessels and is a key driver of age-related cognitive …

Many patients with chest pain undergoing coronary angiography do not show significant
obstructive coronary lesions. A substantial proportion of these patients have abnormalities in …

Purpose Stroke is a disease associated with high mortality. Many inflammatory indicators
such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocyte …

Background: Preservation of brain health has emerged as a leading public health priority for
the aging world population. Advances in neurovascular biology have revealed an intricate …

Lacunar infarcts represent one of the most frequent subtypes of ischemic strokes and may
represent the first recognizable manifestation of a progressive disease of the small …

Abstract Objective Vascular dementia (VaD) is the second most common cause of dementia
and a major health concern worldwide. A comprehensive review on VaD is warranted for …

Vascular contribution to cognitive impairment and dementia (VCID) is a clinical label
encompassing a wide range of cognitive disorders progressing from mild to major vascular …

Hypertension-associated cerebral small vessel disease is a common finding in older people.
Strongly associated with age and hypertension, small vessel disease is found at autopsy in …