[HTML][HTML] Pharmacological mechanism of natural drugs and their active ingredients in the treatment of arrhythmia via calcium channel regulation

X Zhang, Y Gao, Y Zhou, Z Liu, R Liu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Arrhythmia is characterized by abnormal heartbeat rhythms and frequencies caused by
heart pacing and conduction dysfunction. Arrhythmia is the leading cause of death in …

[HTML][HTML] Phytochemicals targeting glycolysis in colorectal cancer therapy: effects and mechanisms of action

L Zhan, F Su, Q Li, Y Wen, F Wei, Z He… - Frontiers in …, 2023 - frontiersin.org
Colorectal cancer (CRC) is the third most common malignant tumor in the world, and it is
prone to recurrence and metastasis during treatment. Aerobic glycolysis is one of the main …

Sophflarine A, a novel matrine-derived alkaloid from Sophora flavescens with therapeutic potential for non-small cell lung cancer through ROS-mediated pyroptosis …

D Luo, X Dai, H Tian, C Fan, H Xie, N Chen, J Wang… - Phytomedicine, 2023 - Elsevier
Background Novel compounds and more efficient treatment options are urgently needed for
the treatment of non-small cell lung cancer (NSCLC). The decoction of Sophora flavescens …

In vivo antibacterial activity of medicinal plant Sophora flavescens against Streptococcus agalactiae infection

FL Zhang, L Yang, WH He, LJ Xie, F Yang… - Journal of Fish …, 2023 - Wiley Online Library
Streptococcosis disease caused by Streptococcus agalactiae (Group B Streptococcus, GBS)
results in a huge economic loss of tilapia culture. It is urgent to find new antimicrobial agents …

A novel type lavandulyl flavonoid from Sophora flavescens as potential anti-hepatic injury agent that inhibit TLR2/NF-κB signaling pathway

Y Lin, XJ Chen, JJ Li, L He, YR Yang, F Zhong… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacology relevance Sophora flavescens Aiton, was a crucial source of
Traditional Chinese Medicine (TCM) that has benefited human health for hundreds of years …

[HTML][HTML] Efficacy and safety of Xian-Lian-Jie-Du optimization decoction as an adjuvant treatment for prevention of recurrence in patients with stage IIIB/IIIC colon …

X Geng, Z Wang, L Feng, Y Gu, R Wang, Q Yao… - … Medicine and Therapies, 2023 - Springer
Introduction Colon cancer remains one of the most prevalent cancers worldwide.
Unfortunately, there are no recognized and effective therapeutic strategies to prevent tumor …

[HTML][HTML] Insecticidal Activities of Sophora flavescens Alt. towards Red Imported Fire Ants (Solenopsis invicta Buren)

Y Tian, Z Zhang - Toxins, 2023 - mdpi.com
The red imported fire ant (Solenopsis invicta) is a worldwide invasive and dangerous insect
that is controlled mainly by chemical insecticides. Plant-derived insecticidal compounds are …

[HTML][HTML] Estrogenic Prenylated Flavonoids in Sophora flavescens

K Nishi, I Imamura, K Hoashi, R Kiyama, S Mitsuiki - Genes, 2024 - mdpi.com
Sophora flavescens is a medicinal herb distributed widely in Japan and it has been used to
treat various diseases and symptoms. To explore its pharmacological use, we examined the …

[HTML][HTML] Osteogenic Activities of Trifolirhizin as a Bioactive Compound for the Differentiation of Osteogenic Cells

HM Yun, MH Cho, H Jeong, SH Kim, YH Jeong… - International Journal of …, 2023 - mdpi.com
Plant extracts are widely used as traditional medicines. Sophora flavescens Aiton-derived
natural compounds exert various beneficial effects, such as anti-inflammatory, anticancer …

[HTML][HTML] Quantitative analysis of active components in Rhodiola species based on disease module-guided network pharmacology

J Zhu, R Jin, M Su, J Pei, Y Chang, M Jiang - Arabian Journal of Chemistry, 2024 - Elsevier
Many different species of Rhodiola are traditional botanical medicines with various effects,
and their roots and rhizomes are the medicinal parts, which have been recorded in many …