Endogenous cardiotonic steroids (CTS), also called digitalis-like factors, have been
postulated to play important roles in health and disease for nearly half a century. Recent …

Non-compliance with drug treatment is widespread. When patients are given medication by
their doctors, nearly half do not take the drug or do not take it as prescribed, and most will …

A general data analysis technique estimates average population values of pharmacokinetic
parameters and their interindividual variability from clinical pharmacokinetic data gathered …

We studied patterns of inhaler usage in a sample of participants from two centers in the Lung
Health Study clinical trial. The inhaler, containing either ipratropium bromide or a placebo …

In research, as well as in daily practice, patient interviews and estimates by clinical staff are
used to determine patients' adherence to drug regimens. The present study was undertaken …

Abstract purpose: To determine the extent of and clinical variables associated with
zidovudine compliance. patients and methods: A survey of 83 patients infected with human …

The aim of this review is to demonstrate why the management of compliance, although not
an explicit feature of the rules of Good Clinical Practice, is essential to the successful …

Automated feedback control methods were applied to a medical problem, in a computer
program that used measured serum digoxin concentrations (as feedback) to predict future …

The administration of digitalis by experienced cardiologists has been examined and a
prototypical computer program has been developed which captures portions of their …

The study is primarily an empirical investigation into patients' thoughts on medicines and
medication. Ninety patients on long-term drug treatment, equally distributed over asthma …