In-vivo Raman spectroscopy: from basics to applications

E Cordero, I Latka, C Matthäus… - Journal of biomedical …, 2018 - spiedigitallibrary.org
For more than two decades, Raman spectroscopy has found widespread use in biological
and medical applications. The instrumentation and the statistical evaluation procedures …

Raman spectroscopy: an emerging tool in neurodegenerative disease research and diagnosis

G Devitt, K Howard, A Mudher… - ACS chemical …, 2018 - ACS Publications
The pathogenesis underlining many neurodegenerative diseases remains incompletely
understood. The lack of effective biomarkers and disease preventative medicine demands …

Classifying breast cancer tissue by Raman spectroscopy with one-dimensional convolutional neural network

D Ma, L Shang, J Tang, Y Bao, J Fu, J Yin - Spectrochimica Acta Part A …, 2021 - Elsevier
As the most common cancer in women, breast cancer is becoming lethal worldwide.
However, the current breast diagnosis technologies are not enough to meet the …

Real-time molecular imaging of near-surface tissue using Raman spectroscopy

W Yang, F Knorr, I Latka, M Vogt… - Light: Science & …, 2022 - nature.com
The steady progress in medical diagnosis and treatment of diseases largely hinges on the
steady development and improvement of modern imaging modalities. Raman spectroscopy …

A new method using Raman spectroscopy for in vivo targeted brain cancer tissue biopsy

J Desroches, M Jermyn, M Pinto, F Picot… - Scientific reports, 2018 - nature.com
Modern cancer diagnosis requires histological, molecular, and genomic tumor analyses.
Tumor sampling is often achieved using a targeted needle biopsy approach. Targeting …

Surface-Enhanced Raman Spectroscopy Biosensing: In Vivo Diagnostics and Multimodal Imaging

AI Henry, B Sharma, MF Cardinal, D Kurouski… - Analytical …, 2016 - ACS Publications
This perspective presents recent developments in the application of surface-enhanced
Raman spectroscopy (SERS) to biosensing, with a focus on in vivo diagnostics. We describe …

Raman spectroscopy for cancer detection and cancer surgery guidance: translation to the clinics

IP Santos, EM Barroso, TCB Schut, PJ Caspers… - Analyst, 2017 - pubs.rsc.org
Oncological applications of Raman spectroscopy have been contemplated, pursued, and
developed at academic level for at least 25 years. Published studies aim to detect pre …

Comparison of surface enhanced Raman spectroscopy and Raman spectroscopy for the detection of breast cancer based on serum samples

HF Nargis, H Nawaz, HN Bhatti, K Jilani… - Spectrochimica Acta Part …, 2021 - Elsevier
In this study, surface enhanced Raman spectroscopy (SERS) and Raman spectroscopy
(RS), are employed for the classification of different stages of breast cancer using clinically …

Open-sourced Raman spectroscopy data processing package implementing a baseline removal algorithm validated from multiple datasets acquired in human tissue …

G Sheehy, F Picot, F Dallaire, K Ember… - Journal of …, 2023 - spiedigitallibrary.org
Significance Standardized data processing approaches are required in the field of bio-
Raman spectroscopy to ensure information associated with spectral data acquired by …

A review of Raman spectroscopy advances with an emphasis on clinical translation challenges in oncology

M Jermyn, J Desroches, K Aubertin… - Physics in Medicine …, 2016 - iopscience.iop.org
There is an urgent need for improved techniques for disease detection. Optical spectroscopy
and imaging technologies have potential for non-or minimally-invasive use in a wide range …