[HTML][HTML] Massively parallel base editing to map variant effects in human hematopoiesis
JD Martin-Rufino, N Castano, M Pang, EI Grody… - Cell, 2023 - cell.com
Systematic evaluation of the impact of genetic variants is critical for the study and treatment
of human physiology and disease. While specific mutations can be introduced by genome …
of human physiology and disease. While specific mutations can be introduced by genome …
[HTML][HTML] Inherited Platelet Disorders: A Short Introduction
B Zieger, D Boeckelmann - Hämostaseologie, 2023 - thieme-connect.com
Platelets play an important role regarding coagulation by contributing to thrombus formation
by platelet adhesion, aggregation, and α-/δ-granule secretion. Inherited platelet disorders …
by platelet adhesion, aggregation, and α-/δ-granule secretion. Inherited platelet disorders …
[HTML][HTML] Recent progress in analyses of GATA1 in hematopoietic disorders: a mini-review
R Shimizu, M Yamamoto - Frontiers in Hematology, 2023 - frontiersin.org
GATA1 is an essential master regulator of erythropoiesis and megakaryopoiesis.
Accumulating lines of evidence have shown that dynamic changes in GATA1 gene …
Accumulating lines of evidence have shown that dynamic changes in GATA1 gene …
A novel GATA1 variant p. G229D causing the defect of procoagulant platelet formation
B Ding, Y Mao, Y Li, M Xin, S Jiang, X Hu, Q Xu… - Thrombosis …, 2024 - Elsevier
Introduction GATA1 is one of the master transcription factors in hematopoietic lineages
development which is crucial for megakaryocytic differentiation and maturation. Previous …
development which is crucial for megakaryocytic differentiation and maturation. Previous …
Aggregates of nonmuscular myosin IIA in erythrocytes associate with GATA1-and GFI1B-related thrombocytopenia
C Zaninetti, L Vater, S Ohlenforst, E Leinøe… - Journal of Thrombosis …, 2024 - Elsevier
Background The transcription factor GATA1 is an essential regulator of erythroid cell gene
expression and maturation and is also relevant for platelet biogenesis. GATA1-related …
expression and maturation and is also relevant for platelet biogenesis. GATA1-related …
[PDF][PDF] Aggregates of nonmuscular myosin IIA in erythrocytes associate with GATA1-and GFI1B-related thrombocytopenia
Background: The transcription factor GATA1 is an essential regulator of erythroid cell gene
expression and maturation and is also relevant for platelet biogenesis. GATA1-related …
expression and maturation and is also relevant for platelet biogenesis. GATA1-related …
GATA1 in Normal and Pathologic Megakaryopoiesis and Platelet Development
K Takasaki, ST Chou - Transcription factors in blood cell development, 2024 - Springer
GATA1 is a highly conserved hematopoietic transcription factor (TF), essential for normal
erythropoiesis and megakaryopoiesis, that encodes a full-length, predominant isoform and …
erythropoiesis and megakaryopoiesis, that encodes a full-length, predominant isoform and …
Células-tronco mesenquimais irradiadas: influência do efeito espectador sobre os controles da hematopoese
RLR Amon - 2024 - teses.usp.br
O processo de hematopoese compreende a produção de células sanguíneas e tem como
protagonista o microambiente hematopoético (MH). No MH tem-se a participação do …
protagonista o microambiente hematopoético (MH). No MH tem-se a participação do …
[PDF][PDF] GATA1-Related Cytopenia GeneReview Table 2–GATA1 Genotype-Phenotype
Title: GATA1-Related Cytopenia GeneReview Table 2 – GATA1 Genotype-Phenotype
Observations Authors: Takasaki K, Kacena MA, Rask Page 1 Title: GATA1-Related Cytopenia …
Observations Authors: Takasaki K, Kacena MA, Rask Page 1 Title: GATA1-Related Cytopenia …