We previously showed that a fall in the plasma free fatty acid (FFA) level increases plasma
corticosterone levels in rats by activating the hypothalamic-pituitary-adrenal axis. In the …

The mechanisms underlying alterations in muscle lipid metabolism in obesity are poorly
understood. The primary aim of this study was to compare the abundance and/or activities of …

For 40 years, the enzyme hormone sensitive lipase was considered to hydrolyze the first
ester bond of the triacylglycerol moiety and thus initiate hydrolysis. However, 12 years ago a …

We hypothesize that a decrease in circulating levels of fatty acid (FA) in rainbow trout
Oncorhynchus mykiss would result in the inhibition of putative hypothalamic FA sensing …

The clinically most relevant medications for lipid management are the statins, which
constitute in the majority of the cases the basis of any lipid-modulating therapy. However …

The aim of the present study was to investigate the influence of substrate availability on fuel
selection during exercise. Eight endurance-trained male cyclists performed 90-min exercise …

The review focuses on scientific evidence responsible for obesity. The role of perilipin in
obesity has been elaborated in detail. The possible causes of obesity and therapeutic …

White adipose tissue is a major energy reserve for the body and is essential for providing
fatty acids for other tissues when needed. Skeletal muscle interleukin-6 (IL-6) has been …

The brain responds to a fall in blood glucose by activating neuroendocrine mechanisms for
its restoration. It is unclear whether the brain also responds to a fall in plasma free fatty acids …

The regulation of fatty acid utilization during muscle contraction and exercise remains to be
fully elucidated. Evidence suggests that the metabolic responses of skeletal muscle induced …