The molecular organization of ribbon synapses in photoreceptors and ON bipolar cells is
reviewed in relation to the process of neurotransmitter release. The interactions between …

Neuromodulators such as dopamine, enable context-dependent plasticity of neural circuit
function throughout the central nervous system. For example, in the retina, dopamine tunes …

Abstract Purpose Retinal ganglion cells (RGCs) are highly susceptible to diabetes-induced
metabolic stress. This study describes the early responses of RGCs to hyperglycemia and …

Ion channels are the gatekeepers to neuronal excitability. Retinal neurons of vertebrates
and invertebrates, neurons of the suprachiasmatic nucleus (SCN) of vertebrates, and …

Over the past 30 years, it has become evident that within the ocular microenvironment there
are active mechanisms of immunoregulation and immunosuppression. The …

Somatostatin acts on specific membrane receptors (sst1–5) to inhibit exocrine and
endocrine functions. The aim was to investigate the distribution of sst1–5 in pancreatic islet …

purpose. To detect the presence of somatostatin (SOM) in normal aqueous humor and to
characterize its immunosuppressive activity. methods. Fresh rabbit aqueous humor was …

An inner retinal microcircuit composed of dopamine (DA)-containing amacrine cells and
melanopsin-containing, intrinsically photosensitive retinal ganglion cells (M1 ipRGCs) …

Neural inhibition plays a key role in determining the specific computational tasks of different
brain circuitries. This functional “braking” activity is provided by inhibitory interneurons that …

In the retina, peptidergic signalling participates in multiple circuits of visual information
processing. The neuropeptide somatostatin (SRIF) is localised to amacrine cells and, in …