Purpose High‐resolution quantitative multi‐parameter mapping shows promise for non‐
invasively characterizing human brain microstructure but is limited by physiological artifacts …

Conduction of action potentials along myelinated axons is affected by their structural
features, such as the axonal g-ratio, the ratio between the inner and outer diameters of the …

The myelin concentration and the degree of myelination of nerve fibers can provide valuable
information on the integrity of human brain tissue. Magnetic resonance imaging (MRI) of …

G-ratio weighted imaging is a non-invasive, in-vivo MRI-based technique that aims at
estimating an aggregated measure of relative myelination of axons across the entire brain …

Neural oscillations at∼ 10 Hz, called alpha oscillations, are one of the most prominent
components of neural oscillations in the human brain. In recent years, characteristics …

Axonal demyelination is a cardinal feature of aging and age-related diseases. The g-ratio,
mathematically defined as the inner-to-outer diameter of a myelinated axon, is used as a …

Abstract Multi-Parameter Mapping (MPM) is a comprehensive quantitative neuroimaging
protocol that enables estimation of four physical parameters (longitudinal and effective …

Diffusion magnetic resonance imaging (MRI) is an increasingly popular technique in basic
and clinical neuroscience. One promising application is to combine diffusion MRI with …

Introduction Relapsing-remitting multiple sclerosis (RRMS) is a chronic, immune-mediated
neurodegenerative disease with a highly heterogeneous disease course. Conventional MRI …

RESULTS: Simulated FLASH multiparameter mapping datasets with increasing noise levels
were analysed with the hMRI toolbox and various processing strategies for PD estimation …