[HTML][HTML] Apoptosis: its origin, history, maintenance and the medical implications for cancer and aging

S Kaczanowski - Physical Biology, 2016 - iopscience.iop.org
Programmed cell death is a basic cellular mechanism. Apoptotic-like programmed cell death
(called apoptosis in animals) occurs in both unicellular and multicellular eukaryotes, and …

Effects of heat on embryos and foetuses

MJ Edwards, RD Saunders, K Shiota - International journal of …, 2003 - Taylor & Francis
Objectives: This paper reviews the effects of elevated maternal temperature on embryo and
foetal development in experimental animals and in humans. Conclusions: Hyperthermia …

[HTML][HTML] Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs

S Tarazi, A Aguilera-Castrejon, C Joubran, N Ghanem… - Cell, 2022 - cell.com
In vitro cultured stem cells with distinct developmental capacities can contribute to
embryonic or extraembryonic tissues after microinjection into pre-implantation mammalian …

Ex utero mouse embryogenesis from pre-gastrulation to late organogenesis

A Aguilera-Castrejon, B Oldak, T Shani, N Ghanem… - Nature, 2021 - nature.com
The mammalian body plan is established shortly after the embryo implants into the maternal
uterus, and our understanding of post-implantation developmental processes remains …

Monitoring of organ formation in rat embryos after in vitro exposure to azathioprine, mercaptopurine, methotrexate or cyclosporin A

BP Schmid - Toxicology, 1984 - Elsevier
Rat embryos in the organ formation phase (days 9.5–11.5 post coitum) were cultivated in
pure rat serum in the presence of an Aroclor 1254 pretreated liver microsomal preparation …

[图书][B] Manipulating the mouse embryo: a laboratory manual

B Hogan, F Costantini, E Lacy - 1986 - genesdev.cshlp.org
The 1986 publication of Manipulating the Mouse Embryo catalyzed the interaction between
molecular biology and mammalian embryology. For the first time, detailed instructions on …

Uterine glands provide histiotrophic nutrition for the human fetus during the first trimester of pregnancy

GJ Burton, AL Watson, J Hempstock… - The Journal of …, 2002 - academic.oup.com
Providing adequate nutrition to the fetus is key to a successful pregnancy. The interstitial
form of implantation displayed by the human blastocyst is generally associated with early …

Vital dye analysis of cranial neural crest cell migration in the mouse embryo

GN Serbedzija, M Bronner-Fraser, SE Fraser - Development, 1992 - journals.biologists.com
The spatial and temporal aspects of cranial neural crest cell migration in the mouse are
poorly understood because of technical limitations. No reliable cell markers are available …

Quantitation of rat embryonic development in vitro: a morphological scoring system

NA Brown, S Fabro - Teratology, 1981 - Wiley Online Library
In order to realize the maximum potential of whole‐embryo culture techniques, definitive
parameters must be developed for the quantitative estimation of embryonic growth and …

Death before birth: clues from gene knockouts and mutations

AJ Copp - Trends in Genetics, 1995 - cell.com
A survey of mouse gene knockouts, transgene insertions and spontaneous mutations that
are lethal prenatally reveals that surprisingly few developmental disturbances lead to death …