Epigenetic regulation in chromium-, nickel-and cadmium-induced carcinogenesis

L Zhao, R Islam, Y Wang, X Zhang, LZ Liu - Cancers, 2022 - mdpi.com
Simple Summary Environmental and occupational exposure to heavy metals are risk factors
for cancers. However, the molecular mechanisms of how heavy metals induce …

Inflammatory effects of hexavalent chromium in the lung: A comprehensive review

JC Kouokam, I Meaza, JP Wise Sr - Toxicology and applied pharmacology, 2022 - Elsevier
Besides smoking, lung cancer can be caused by other factors, including heavy metals such
as cadmium, nickel, arsenic, beryllium and hexavalent chromium [Cr (VI)], which is used in …

Epigenetic and epitranscriptomic mechanisms of chromium carcinogenesis

Z Wang, C Yang - Advances in Pharmacology, 2023 - Elsevier
Abstract Hexavalent chromium [Cr (VI)], a Group I carcinogen classified by the International
Agency for Research on Cancer (IARC), represents one of the most common occupational …

Hexavalent chromium targets securin to drive numerical chromosome instability in human lung cells

JH Toyoda, J Martino, RM Speer, I Meaza, H Lu… - International Journal of …, 2023 - mdpi.com
Hexavalent chromium [Cr (VI)] is a known human lung carcinogen with widespread
exposure in environmental and occupational settings. Despite well-known cancer risks, the …

Potential mechanisms of lung injury and repair after hexavalent chromium [Cr (VI)] aerosol whole-body dynamic exposure

C Long, Z Su, G Hu, Q Zhang, Y Zhang, T Chen… - Chemosphere, 2024 - Elsevier
Abstract Hexavalent chromium [Cr (VI)], known as" Top Hazardous Substances", poses a
significant threat to the respiratory system. Nevertheless, the potential mechanisms of toxicity …

Detoxification and resource utilization of soda ash chromite ore processing residue by copper slag

L Wang, Y Xu, Y Ma, Y Chen, A Yang, G Gan… - Process Safety and …, 2023 - Elsevier
Chromite ore processing residue (COPR) and copper slag (CS) are industrial waste slags
that cause environmental pollution and require effective treatment. This study proposes a …

Prolonged particulate hexavalent chromium exposure induces RAD51 foci inhibition and cytoplasmic accumulation in immortalized and primary human lung bronchial …

I Meaza, AR Williams, H Lu, JC Kouokam… - Toxicology and Applied …, 2023 - Elsevier
Abstract Hexavalent chromium [Cr (VI)] is a human lung carcinogen with widespread
exposure risks. Cr (VI) causes DNA double strand breaks that if unrepaired, progress into …

Prolonged Particulate Hexavalent Chromium Exposure Induces DNA Double-Strand Breaks and Inhibits Homologous Recombination Repair in Primary Rodent Lung …

JTF Wise, H Lu, I Meaza, SS Wise, AR Williams… - … Trace Element Research, 2024 - Springer
Abstract Hexavalent chromium [Cr (VI)] is a known lung carcinogen and a driving
mechanism in human lung cells for Cr (VI)-induced lung cancer is chromosome instability …

Transcriptomic analysis reveals particulate hexavalent chromium regulates key inflammatory pathways in human lung fibroblasts as a possible mechanism of …

JC Kouokam, RM Speer, I Meaza, JH Toyoda… - Toxicology and Applied …, 2024 - Elsevier
Abstract Hexavalent chromium [Cr (VI)] is considered a major environmental health concern
and lung carcinogen. However, the exact mechanism by which Cr (VI) causes lung cancer in …

[PDF][PDF] Epigenetic Regulation in Chromium-, Nickel-and Cadmium-Induced Carcinogenesis. Cancers 2022, 14, 5768

L Zhao, R Islam, Y Wang, X Zhang, LZ Liu - 2022 - researchgate.net
Environmental and occupational exposure to heavy metals, such as hexavalent chromium,
nickel, and cadmium, are major health concerns worldwide. Some heavy metals are well …