A tale of two cancers: A current concise overview of breast and prostate cancer

F De Silva, J Alcorn - Cancers, 2022 - mdpi.com
Simple Summary Breast and prostate cancers are serious public health issues that create
considerable burden to both people and healthcare systems worldwide. Cancer is a …

PAD4 and its inhibitors in cancer progression and prognosis

D Zhu, Y Lu, Y Wang, Y Wang - Pharmaceutics, 2022 - mdpi.com
The systemic spread of malignancies and the risk of cancer-associated thrombosis are
major clinical challenges in cancer therapy worldwide. As an important post-translational …

BRD9-mediated control of the TGF-β/Activin/Nodal pathway regulates self-renewal and differentiation of human embryonic stem cells and progression of cancer cells

X Wang, C Song, Y Ye, Y Gu, X Li, P Chen… - Nucleic Acids …, 2023 - academic.oup.com
Abstract Bromodomain-containing protein 9 (BRD9) is a specific subunit of the non-
canonical SWI/SNF (ncBAF) chromatin-remodeling complex, whose function in human …

Merits and challenges of iPSC-derived organoids for clinical applications

Z Xu, J Yang, X Xin, C Liu, L Li, X Mei… - Frontiers in Cell and …, 2023 - frontiersin.org
Induced pluripotent stem cells (iPSCs) have entered an unprecedented state of
development since they were first generated. They have played a critical role in disease …

Instigation of the epoch of nanovaccines in cancer immunotherapy

S Shah, P Famta, V Tiwari, AK Kotha… - Wiley …, 2023 - Wiley Online Library
Cancer is an unprecedented proliferation of cells leading to abnormalities in differentiation
and maturation. Treatment of primary and metastatic cancer is challenging. In addition to …

Therapeutic potential of human stem cell implantation in alzheimer's disease

HJ Chan, Yanshree, J Roy, GL Tipoe, ML Fung… - International journal of …, 2021 - mdpi.com
Alzheimer's disease (AD) is a progressive debilitating neurodegenerative disease and the
most common form of dementia in the older population. At present, there is no definitive …

[HTML][HTML] Strategies to safely use cryopreserved ovarian tissue to restore fertility after cancer: A systematic review

L Eijkenboom, E Saedt, C Zietse, D Braat… - Reproductive …, 2022 - Elsevier
Ovarian tissue cryopreservation and subsequent autotransplantation is a successful
technique for fertility preservation in oncological patients. However, there are concerns …

AKT1 induces Nanog promoter in a SUMOylation-dependent manner in different pluripotent contexts

MG Francia, P Verneri, C Oses… - BMC Research …, 2023 - Springer
AKT/PKB is a kinase crucial for pluripotency maintenance in pluripotent stem cells. Multiple
post-translational modifications modulate its activity. We have previously demonstrated that …

Clinical applications of pluripotent stem cells and their derivatives: current status and future perspectives

S Pendse, A Vaidya, V Kale - Regenerative Medicine, 2022 - Taylor & Francis
Pluripotent stem cells (PSCs) can differentiate into specific cell types and thus hold great
promise in regenerative medicine to treat certain diseases. Hence, several studies have …

Investigating the mechanisms underlying resistance to chemoterapy and to CRISPR-Cas9 in cancer cell lines

F Tomasi, M Pozzi, M Lauria - Scientific Reports, 2024 - nature.com
Cancer is one of the major causes of death worldwide and the development of multidrug
resistance (MDR) in cancer cells is the principal cause of chemotherapy failure. To gain …