A tale of two cancers: A current concise overview of breast and prostate cancer
F De Silva, J Alcorn - Cancers, 2022 - mdpi.com
Simple Summary Breast and prostate cancers are serious public health issues that create
considerable burden to both people and healthcare systems worldwide. Cancer is a …
considerable burden to both people and healthcare systems worldwide. Cancer is a …
PAD4 and its inhibitors in cancer progression and prognosis
D Zhu, Y Lu, Y Wang, Y Wang - Pharmaceutics, 2022 - mdpi.com
The systemic spread of malignancies and the risk of cancer-associated thrombosis are
major clinical challenges in cancer therapy worldwide. As an important post-translational …
major clinical challenges in cancer therapy worldwide. As an important post-translational …
BRD9-mediated control of the TGF-β/Activin/Nodal pathway regulates self-renewal and differentiation of human embryonic stem cells and progression of cancer cells
X Wang, C Song, Y Ye, Y Gu, X Li, P Chen… - Nucleic Acids …, 2023 - academic.oup.com
Abstract Bromodomain-containing protein 9 (BRD9) is a specific subunit of the non-
canonical SWI/SNF (ncBAF) chromatin-remodeling complex, whose function in human …
canonical SWI/SNF (ncBAF) chromatin-remodeling complex, whose function in human …
Merits and challenges of iPSC-derived organoids for clinical applications
Z Xu, J Yang, X Xin, C Liu, L Li, X Mei… - Frontiers in Cell and …, 2023 - frontiersin.org
Induced pluripotent stem cells (iPSCs) have entered an unprecedented state of
development since they were first generated. They have played a critical role in disease …
development since they were first generated. They have played a critical role in disease …
Instigation of the epoch of nanovaccines in cancer immunotherapy
Cancer is an unprecedented proliferation of cells leading to abnormalities in differentiation
and maturation. Treatment of primary and metastatic cancer is challenging. In addition to …
and maturation. Treatment of primary and metastatic cancer is challenging. In addition to …
Therapeutic potential of human stem cell implantation in alzheimer's disease
HJ Chan, Yanshree, J Roy, GL Tipoe, ML Fung… - International journal of …, 2021 - mdpi.com
Alzheimer's disease (AD) is a progressive debilitating neurodegenerative disease and the
most common form of dementia in the older population. At present, there is no definitive …
most common form of dementia in the older population. At present, there is no definitive …
[HTML][HTML] Strategies to safely use cryopreserved ovarian tissue to restore fertility after cancer: A systematic review
L Eijkenboom, E Saedt, C Zietse, D Braat… - Reproductive …, 2022 - Elsevier
Ovarian tissue cryopreservation and subsequent autotransplantation is a successful
technique for fertility preservation in oncological patients. However, there are concerns …
technique for fertility preservation in oncological patients. However, there are concerns …
AKT1 induces Nanog promoter in a SUMOylation-dependent manner in different pluripotent contexts
MG Francia, P Verneri, C Oses… - BMC Research …, 2023 - Springer
AKT/PKB is a kinase crucial for pluripotency maintenance in pluripotent stem cells. Multiple
post-translational modifications modulate its activity. We have previously demonstrated that …
post-translational modifications modulate its activity. We have previously demonstrated that …
Clinical applications of pluripotent stem cells and their derivatives: current status and future perspectives
Pluripotent stem cells (PSCs) can differentiate into specific cell types and thus hold great
promise in regenerative medicine to treat certain diseases. Hence, several studies have …
promise in regenerative medicine to treat certain diseases. Hence, several studies have …
Investigating the mechanisms underlying resistance to chemoterapy and to CRISPR-Cas9 in cancer cell lines
Cancer is one of the major causes of death worldwide and the development of multidrug
resistance (MDR) in cancer cells is the principal cause of chemotherapy failure. To gain …
resistance (MDR) in cancer cells is the principal cause of chemotherapy failure. To gain …