[HTML][HTML] Hallmarks of neurodegenerative diseases
DM Wilson, MR Cookson, L Van Den Bosch… - Cell, 2023 - cell.com
Decades of research have identified genetic factors and biochemical pathways involved in
neurodegenerative diseases (NDDs). We present evidence for the following eight hallmarks …
neurodegenerative diseases (NDDs). We present evidence for the following eight hallmarks …
Supramolecular adhesive hydrogels for tissue engineering applications
Tissue engineering is a promising and revolutionary strategy to treat patients who suffer the
loss or failure of an organ or tissue, with the aim to restore the dysfunctional tissues and …
loss or failure of an organ or tissue, with the aim to restore the dysfunctional tissues and …
[HTML][HTML] Walking naturally after spinal cord injury using a brain–spine interface
H Lorach, A Galvez, V Spagnolo, F Martel, S Karakas… - Nature, 2023 - nature.com
A spinal cord injury interrupts the communication between the brain and the region of the
spinal cord that produces walking, leading to paralysis,. Here, we restored this …
spinal cord that produces walking, leading to paralysis,. Here, we restored this …
[HTML][HTML] Spinal cord injury: molecular mechanisms and therapeutic interventions
X Hu, W Xu, Y Ren, Z Wang, X He, R Huang… - Signal transduction and …, 2023 - nature.com
Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the …
The challenges of SCI repair include its complex pathological mechanisms and the …
Exosomes‐loaded Electroconductive hydrogel synergistically promotes tissue repair after spinal cord injury via Immunoregulation and enhancement of myelinated …
L Fan, C Liu, X Chen, L Zheng, Y Zou, H Wen… - Advanced …, 2022 - Wiley Online Library
Electroconductive hydrogels are very attractive candidates for accelerated spinal cord injury
(SCI) repair because they match the electrical and mechanical properties of neural tissue …
(SCI) repair because they match the electrical and mechanical properties of neural tissue …
Bioactive scaffolds with enhanced supramolecular motion promote recovery from spinal cord injury
The signaling of cells by scaffolds of synthetic molecules that mimic proteins is known to be
effective in the regeneration of tissues. Here, we describe peptide amphiphile …
effective in the regeneration of tissues. Here, we describe peptide amphiphile …
Cell-based and stem-cell-based treatments for spinal cord injury: evidence from clinical trials
Spinal cord injury is a severely disabling neurological condition leading to impaired mobility,
pain, and autonomic dysfunction. Most often, a single traumatic event, such as a traffic or …
pain, and autonomic dysfunction. Most often, a single traumatic event, such as a traffic or …
An injectable rapid‐adhesion and anti‐swelling adhesive hydrogel for hemostasis and wound sealing
S Bian, L Hao, X Qiu, J Wu, H Chang… - Advanced Functional …, 2022 - Wiley Online Library
Injectable hydrogel adhesives integrating both rapid adhesion to wet tissues and anti‐
swelling in humid environments are highly desired for fast hemostasis and wound sealing in …
swelling in humid environments are highly desired for fast hemostasis and wound sealing in …
The influence of timing of surgical decompression for acute spinal cord injury: a pooled analysis of individual patient data
JH Badhiwala, JR Wilson, CD Witiw, JS Harrop… - The Lancet …, 2021 - thelancet.com
Background Although there is a strong biological rationale for early decompression of the
injured spinal cord, the influence of the timing of surgical decompression for acute spinal …
injured spinal cord, the influence of the timing of surgical decompression for acute spinal …
[HTML][HTML] Moving beyond the glial scar for spinal cord repair
EJ Bradbury, ER Burnside - Nature communications, 2019 - nature.com
Traumatic spinal cord injury results in severe and irreversible loss of function. The injury
triggers a complex cascade of inflammatory and pathological processes, culminating in …
triggers a complex cascade of inflammatory and pathological processes, culminating in …