Sáez, Juan C., Viviana M. Berthoud, María C. Brañes, Agustín D. Martínez, and Eric C.
Beyer. Plasma Membrane Channels Formed by Connexins: Their Regulation and Functions …

Gap junctions are plasma membrane spatial microdomains constructed of assemblies of
channel proteins called connexins in vertebrates and innexins in invertebrates. The …

Ion channels are membrane proteins that act as gated pathways for the movement of ions
across cell membranes. They play essential roles in the physiology of all cells. In recent …

Gap junctions are membrane structures made of intercellular channels which permit the
diffusion from cytoplasm to cytoplasm of small hydrophilic molecules. Nearly 40 years ago …

Inherited neuropathies known as Charcot-Marie-Tooth (CMT) disease are genetically
heterogeneous disorders affecting the peripheral nerves, causing significant and slowly …

▪ Abstract Intercellular channels present in gap junctions allow cells to share small
molecules and thus coordinate a wide range of behaviors. Remarkably, although junctions …

The fundamental roles of Schwann cells during peripheral nerve formation and regeneration
have been recognized for more than 100 years, but the cellular and molecular mechanisms …

Mutations in the gene encoding the gap junction protein connexin32 (Cx32) cause X‐linked
Charcot‐Marie‐Tooth disease (CMTX), a common form of inherited demyelinating …

Mutations affecting the connexin 32 (Cx32) gene are associated with the X-linked form of the
hereditary peripheral neuropathy Charcot–Marie–Tooth disease (CMTX). We show that …

Abstract Charcot‐Marie‐Tooth disease (CMT) is a genetically heterogeneous disorder that
has been associated with alterations of several proteins: peripheral myelin protein 22 …