The multifaceted nature of antimicrobial peptides: Current synthetic chemistry approaches and future directions

BH Gan, J Gaynord, SM Rowe, T Deingruber… - Chemical Society …, 2021 - pubs.rsc.org
Bacterial infections caused by 'superbugs' are increasing globally, and conventional
antibiotics are becoming less effective against these bacteria, such that we risk entering a …

Antimicrobial peptides: an update on classifications and databases

A Bin Hafeez, X Jiang, PJ Bergen, Y Zhu - International journal of …, 2021 - mdpi.com
Antimicrobial peptides (AMPs) are distributed across all kingdoms of life and are an
indispensable component of host defenses. They consist of predominantly short cationic …

Inflammatory response mechanisms of the dentine–pulp complex and the periapical tissues

KM Galler, M Weber, Y Korkmaz, M Widbiller… - International journal of …, 2021 - mdpi.com
The macroscopic and microscopic anatomy of the oral cavity is complex and unique in the
human body. Soft-tissue structures are in close interaction with mineralized bone, but also …

Antimicrobial peptides (AMPs): Ancient compounds that represent novel weapons in the fight against bacteria

JM Ageitos, A Sánchez-Pérez, P Calo-Mata… - Biochemical …, 2017 - Elsevier
Antimicrobial peptides (AMPs) are short peptidic molecules produced by most living
creatures. They help unicellular organisms to successfully compete for nutrients with other …

Defensins: The natural peptide antibiotic

X Gao, J Ding, C Liao, J Xu, X Liu, W Lu - Advanced drug delivery reviews, 2021 - Elsevier
Defensins are a family of cationic antimicrobial peptides active against a broad range of
infectious microbes including bacteria, viruses and fungi, playing important roles as innate …

Dental pulp defence and repair mechanisms in dental caries

JC Farges, B Alliot-Licht, E Renard… - Mediators of …, 2015 - Wiley Online Library
Dental caries is a chronic infectious disease resulting from the penetration of oral bacteria
into the enamel and dentin. Microorganisms subsequently trigger inflammatory responses in …

Defensins: a double-edged sword in host immunity

D Xu, W Lu - Frontiers in immunology, 2020 - frontiersin.org
Defensins are a major family of host defense peptides expressed predominantly in
neutrophils and epithelial cells. Their broad antimicrobial activities and multifaceted …

Physiologic hypoxia and oxygen homeostasis in the healthy intestine. A review in the theme: cellular responses to hypoxia

L Zheng, CJ Kelly, SP Colgan - American Journal of …, 2015 - journals.physiology.org
In recent years, the intestinal mucosa has proven to be an intriguing organ to study tissue
oxygenation. The highly vascularized lamina propria juxtaposed to an anaerobic lumen …

Immunomodulatory and allergenic properties of antimicrobial peptides

SV Guryanova, TV Ovchinnikova - International journal of molecular …, 2022 - mdpi.com
With the growing problem of the emergence of antibiotic-resistant bacteria, the search for
alternative ways to combat bacterial infections is extremely urgent. While analyzing the effect …

[HTML][HTML] Biomimetic peptide dynamic hydrogel inspired by humanized defensin nanonets as the wound-healing gel coating

J Yuan, Y Wang, W Yang, X Li, K Tao, W He… - Chemical Engineering …, 2023 - Elsevier
Clinical treatment of chronic wounds, particularly those prone to relapse, has been
hampered by the regeneration, infection complications, and malignant transformation of …