Among non-conventional yeasts of industrial interest, the dimorphic oleaginous yeast
Yarrowia lipolytica appears as one of the most attractive for a large range of white …

Genetically encoded biosensors are the vital components of synthetic biology and metabolic
engineering, as they are regarded as powerful devices for the dynamic control of genotype …

Due to the ability to regulate target metabolic pathways globally and dynamically, metabolic
regulation systems composed of transcription factors have been widely used in metabolic …

Metabolic engineering seeks to rewire the metabolic network of cells for the efficient
production of value-added compounds from renewable substrates. However, it remains …

Sugar alcohols are polyols that are widely employed in the production of chemicals,
pharmaceuticals, and food products. Chemical synthesis of polyols, however, is complex …

Food additives and colorants are extensively used in the food industry to improve food
quality and safety during processing, storage and packing. Sourcing of these molecules is …

Natural products and their derivatives offer a rich source of chemical and biological diversity;
however, traditional engineering of their biosynthetic pathways to improve yields and access …

Yarrowia lipolytica is an oleaginous yeast that has been substantially engineered for
production of oleochemicals and drop-in transportation fuels. The unique acetyl …

Abstract Development of microbial cell factory for L-tryptophan (L-trp) production has
received widespread attention but still requires extensive efforts due to weak metabolic flux …

Microbes can convert inexpensive renewable substrates to valuable metabolites by their
natural metabolic pathways. To maximize the productivity, the pathways yet require further …