Abstract Interleukin-10 (IL-10) is an important immunoregulatory cytokine. The recent
characterisation of the proximal 5′ flanking region of IL-10 led to the identification of the …

Systemic Lupus Erythematosus (SLE) is one of the most relevant world-wide autoimmune
disorders. The formation of autoantibodies and the deposition of antibody-containing …

Behçet's disease (BD) is a multisystem inflammatory disease characterized by recurrent
orogenital ulceration, ocular inflammation, and skin lesions. The etiology of the disease is …

Although aspirin-exacerbated respiratory disease (AERD) has attracted a great deal of
attention because of its association with severe asthma, it remains widely under-diagnosed …

Asthma represents a profound worldwide public health problem. The most effective anti-
asthmatic drugs currently available include inhaled β2-agonists and glucocorticoids and …

We analyzed polymorphisms of IL‐10− 1082 G/A, IL‐18− 137 G/C, TLR4+ 896 A/G, and
IFNG+ 874 T/A in 139 infants under 6 months of age hospitalized with bronchiolitis and 400 …

Abundant evidence suggests that cytokines involve in the pathogenesis of latent
autoimmune diabetes of adults (LADA). This is a slowly progressive form of type 1 diabetes …

Allergic diseases are caused by the induction of T helper (Th) 2 cells and IgE responses
specific for common environmental antigens (allergens) in susceptible individuals. There is …

Interleukin (IL)-10 and IL-12 production is decreased in peripheral blood mononuclear cells
of patients with mild asthma. Using whole blood culture and flow cytometry we examined …

The main focus of this review was the role of a specific subset of T cells with
immunomodulatory or immunosuppressive activities, termed regulatory T cells (Tregs), in the …