Review of toxicity studies of carbon nanotubes

N Kobayashi, H Izumi… - Journal of occupational …, 2017 - Wiley Online Library
Objective We reviewed studies on pulmonary, reproductive, and developmental toxicity
caused by carbon nanotubes (CNTs). In paricular, we analyzed how CNT exposure affects …

Carbon nanotubes in biomedical applications: factors, mechanisms, and remedies of toxicity: miniperspective

R Alshehri, AM Ilyas, A Hasan, A Arnaout… - Journal of medicinal …, 2016 - ACS Publications
Carbon nanotubes (CNTs) represent one of the most studied allotropes of carbon. The
unique physicochemical properties of CNTs make them among prime candidates for …

Lung carcinogenicity of inhaled multi-walled carbon nanotube in rats

T Kasai, Y Umeda, M Ohnishi, T Mine, H Kondo… - Particle and Fibre …, 2015 - Springer
Background Multi-walled carbon nanotubes (MWCNTs) constitute one of the most promising
types of nanomaterials in industry today. With their increasing use, the potential toxicity and …

Malignant pleural mesothelioma: history, controversy, and future of a man-made epidemic

OD Røe, GM Stella - Asbestos and Mesothelioma, 2017 - Springer
Asbestos (Greek, inextinguishable) is the term of a family of naturally occurring minerals that
have been used in small scale since ancient times. Industrialization demanded increased …

Advances in mechanisms and signaling pathways of carbon nanotube toxicity

J Dong, Q Ma - Nanotoxicology, 2015 - Taylor & Francis
Carbon nanotubes (CNT) have been developed into new materials with a variety of
industrial and commercial applications. In contrast, the physicochemical properties of CNT at …

Genotoxicity of multi-walled carbon nanotubes at occupationally relevant doses

KJ Siegrist, SH Reynolds, ML Kashon… - Particle and fibre …, 2014 - Springer
Carbon nanotubes are commercially-important products of nanotechnology; however, their
low density and small size makes carbon nanotube respiratory exposures likely during their …

Genotoxicity assessment of nanomaterials: recommendations on best practices, assays, and methods

R Elespuru, S Pfuhler, MJ Aardema… - Toxicological …, 2018 - academic.oup.com
Nanomaterials (NMs) present unique challenges in safety evaluation. An international
working group, the Genetic Toxicology Technical Committee of the International Life …

Genotoxicity and carcinogenicity risk of carbon nanotubes

S Toyokuni - Advanced Drug Delivery Reviews, 2013 - Elsevier
Novel materials are often commercialized without a complete assessment of the risks they
pose to human health because such assessments are costly and time-consuming; …

Lung recovery from DNA damage induced by graphene oxide is dependent on size, dose and inflammation profile

LAV De Luna, T Loret, A Fordham, A Arshad… - Particle and fibre …, 2022 - Springer
Background A key aspect of any new material safety assessment is the evaluation of their in
vivo genotoxicity. Graphene oxide (GO) has been studied for many promising applications …

Evaluating the mechanistic evidence and key data gaps in assessing the potential carcinogenicity of carbon nanotubes and nanofibers in humans

ED Kuempel, MC Jaurand, P Møller… - Critical reviews in …, 2017 - Taylor & Francis
In an evaluation of carbon nanotubes (CNTs) for the IARC Monograph 111, the Mechanisms
Subgroup was tasked with assessing the strength of evidence on the potential …