[HTML][HTML] The transdermal delivery of therapeutic cannabinoids

H Mahmoudinoodezh, SR Telukutla, SK Bhangu… - Pharmaceutics, 2022 - mdpi.com
Recently, several studies have indicated an increased interest in the scientific community
regarding the application of Cannabis sativa plants, and their extracts, for medicinal …

Nanoformulations as a strategy to overcome the delivery limitations of cannabinoids

TS Reddy, R Zomer, N Mantri - Phytotherapy Research, 2023 - Wiley Online Library
Medical cannabis has received significant interest in recent years due to its promising
benefits in the management of pain, anxiety, depression and neurological and movement …

[HTML][HTML] Cannabidiol alters mitochondrial bioenergetics via VDAC1 and triggers cell death in hormone-refractory prostate cancer

AM Mahmoud, M Kostrzewa, V Marolda… - Pharmacological …, 2023 - Elsevier
In spite of the huge advancements in both diagnosis and interventions, hormone refractory
prostate cancer (HRPC) remains a major hurdle in prostate cancer (PCa). Metabolic …

Cannabinoids as immune system modulators: Cannabidiol potential therapeutic approaches and limitations

A Aziz, LC Nguyen, L Oumeslakht… - Cannabis and …, 2023 - liebertpub.com
Introduction: Cannabidiol (CBD) is the second most abundant Phytocannabinoid in
Cannabis extracts. CBD has a binding affinity for several cannabinoid and cannabinoid …

The evolution of cannabinoid receptors in cancer

NM Pennant, CV Hinton - WIREs mechanisms of disease, 2023 - Wiley Online Library
Cannabis sativa (cannabis) has been used as a therapeutic treatment for centuries treating
various diseases and disorders. However, racial propaganda led to the criminalization of …

[HTML][HTML] Potential, limitations and risks of cannabis-derived products in cancer treatment

HJ Woerdenbag, P Olinga, EA Kok, DAP Brugman… - Cancers, 2023 - mdpi.com
Simple Summary It is easy to find success stories on the internet of patients with cancer who
seem to benefit from using cannabis products. However, scientific substantiation is usually …

[HTML][HTML] Molecular mechanism of tanshinone against prostate cancer

W Li, T Huang, S Xu, B Che, Y Yu, W Zhang, K Tang - Molecules, 2022 - mdpi.com
Prostate cancer (PCa) is the most common malignant tumor of the male urinary system in
Europe and America. According to the data in the World Cancer Report 2020, the incidence …

[HTML][HTML] Post-harvest operations to generate high-quality medicinal Cannabis products: A systemic review

HMS Al Ubeed, RBH Wills, J Chandrapala - Molecules, 2022 - mdpi.com
The traditional Cannabis plant as a medicinal crop has been explored for many thousands
of years. The Cannabis industry is rapidly growing; therefore, optimising drying methods and …

Rationalizing a prospective coupling effect of cannabinoids with the current pharmacotherapy for melanoma treatment

A Bachari, N Nassar, E Schanknecht… - WIREs Mechanisms …, 2024 - Wiley Online Library
Melanoma is one of the leading fatal forms of cancer, yet from a treatment perspective, we
have minimal control over its reoccurrence and resistance to current pharmacotherapies …

[HTML][HTML] Cannabidiol and Cannabis Sativa as a potential treatment in vitro prostate cancer cells silenced with RBBp6 and PC3 xenograft

LR Motadi, ZE Jantjies, B Moleya - Molecular biology reports, 2023 - Springer
Background Prostate cancer is the second most frequently occurring carcinoma in males
worldwide and one of the leading causes of death in men around the world. Recent studies …