Macrophage-targeted nanomedicine for the diagnosis and treatment of atherosclerosis

W Chen, M Schilperoort, Y Cao, J Shi, I Tabas… - Nature Reviews …, 2022 - nature.com
Nanotechnology could improve our understanding of the pathophysiology of atherosclerosis
and contribute to the development of novel diagnostic and therapeutic strategies to further …

Recent applications of immunomodulatory biomaterials for disease immunotherapy

H Dai, Q Fan, C Wang - Exploration, 2022 - Wiley Online Library
Immunotherapy is used to regulate systemic hyperactivation or hypoactivation to treat
various diseases. Biomaterial‐based immunotherapy systems can improve therapeutic …

A photo-triggered self-accelerated nanoplatform for multifunctional image-guided combination cancer immunotherapy

X Kang, Y Zhang, J Song, L Wang, W Li, J Qi… - Nature …, 2023 - nature.com
Precise and efficient image-guided immunotherapy holds great promise for cancer
treatment. Here, we report a self-accelerated nanoplatform combining an aggregation …

Cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles

L Liu, X Bai, MV Martikainen, A Kårlund… - Nature …, 2021 - nature.com
Cell membrane coated nanoparticles (NPs) have recently been recognized as attractive
nanomedical tools because of their unique properties such as immune escape, long blood …

Cancer cell-mitochondria hybrid membrane coated Gboxin loaded nanomedicines for glioblastoma treatment

Y Zou, Y Sun, Y Wang, D Zhang, H Yang… - Nature …, 2023 - nature.com
Glioblastoma (GBM) remains the most lethal malignant tumours. Gboxin, an oxidative
phosphorylation inhibitor, specifically restrains GBM growth by inhibiting the activity of F0F1 …

A metal-organic framework-based immunomodulatory nanoplatform for anti-atherosclerosis treatment

Z Xu, Z Wu, S Huang, K Ye, Y Jiang, J Liu, J Liu… - Journal of Controlled …, 2023 - Elsevier
Immunomodulatory therapy has become a promising method for the clinical treatment of
many diseases. Recently, pilot studies revealed that immunomodulatory therapy exhibited …

[HTML][HTML] Macrophage membrane functionalized biomimetic nanoparticles for targeted anti-atherosclerosis applications

Y Wang, K Zhang, T Li, A Maruf, X Qin, L Luo… - Theranostics, 2021 - ncbi.nlm.nih.gov
Atherosclerosis (AS), the underlying cause of most cardiovascular events, is one of the most
common causes of human morbidity and mortality worldwide due to the lack of an efficient …

Macrophage membrane-camouflaged responsive polymer nanogels enable magnetic resonance imaging-guided chemotherapy/chemodynamic therapy of orthotopic …

T Xiao, M He, F Xu, Y Fan, B Jia, M Shen, H Wang… - ACS …, 2021 - ACS Publications
Development of innovative nanomedicine formulations to traverse the blood–brain barrier
(BBB) for effective theranostics of glioma remains a great challenge. Herein, we report the …

Macrophage cell membrane-based nanoparticles: a new promising biomimetic platform for targeted delivery and treatment

Y Wu, S Wan, S Yang, H Hu, C Zhang, J Lai… - Journal of …, 2022 - Springer
Synthetic nanoparticles with surface bioconjugation are promising platforms for targeted
therapy, but their simple biological functionalization is still a challenging task against the …

Living macrophage-delivered tetrapod PdH nanoenzyme for targeted atherosclerosis management by ROS scavenging, hydrogen anti-inflammation, and autophagy …

R Hu, C Dai, C Dong, L Ding, H Huang, Y Chen… - ACS …, 2022 - ACS Publications
Atherosclerosis, driven by chronic inflammation in the artery walls, underlies several severe
cardiovascular diseases. However, currently available anti-inflammatory-based strategies …