The combination of spatial transcriptomics (ST) and single cell RNA sequencing (scRNA-
seq) acts as a pivotal component to bridge the pathological phenomes of human tissues with …

COVID-19 is a primary respiratory illness that is frequently complicated by systemic
involvement of the vasculature. Vascular involvement leads to an array of complications …

Here, we recorded serum proteome profiles of 33 severe COVID-19 patients admitted to
respiratory and intensive care units because of respiratory failure. We received, for most …

The pulmonary endothelium is a highly regulated organ that performs a wide range of
functions under physiological and pathological conditions. Since endothelial dysfunction …

Background Some COVID-19 survivors present lung function abnormalities during follow-up,
particularly reduced carbon monoxide lung diffusing capacity (DLCO). To investigate risk …

Several studies suggested the association of COVID-19 with systemic oxidative stress, in
particular with lipid peroxidation and vascular stress. Therefore, this study aimed to evaluate …

The COVID-19 pandemic has highlighted the need for human respiratory tract-based assay
platforms for efficient discovery and development of antivirals and disease-modulating …

In late 2019, a new member of the Coronaviridae family, officially designated as “severe
acute respiratory syndrome coronavirus 2”(SARS-CoV-2), emerged and spread rapidly. The …

Endothelial damage is recognized as the initial step that precedes several cardiovascular
diseases (CVD), such as atherosclerosis, hypertension, and coronary artery disease. It has …

Highlights What are the main findings? Understanding of mutations provides structural
insight into SARS-CoV-2 variants; Comparison of mutations narrates the common and …