[HTML][HTML] Pyoderma gangrenosum: an updated literature review on established and emerging pharmacological treatments

CA Maronese, MA Pimentel, MM Li… - American Journal of …, 2022 - Springer
Pyoderma gangrenosum is a rare inflammatory skin disease classified within the group of
neutrophilic dermatoses and clinically characterized by painful, rapidly evolving cutaneous …

[HTML][HTML] Risk factors for the development of psoriasis

K Kamiya, M Kishimoto, J Sugai, M Komine… - International journal of …, 2019 - mdpi.com
Psoriasis is an immune-mediated genetic skin disease. The underlying pathomechanisms
involve complex interaction between the innate and adaptive immune system. T cells …

[HTML][HTML] Bullous pemphigoid: trigger and predisposing factors

F Moro, L Fania, JLM Sinagra, A Salemme, G Di Zenzo - Biomolecules, 2020 - mdpi.com
Bullous pemphigoid (BP) is the most frequent autoimmune subepidermal blistering disease
provoked by autoantibodies directed against two hemidesmosomal proteins: BP180 and …

Global prevalence and bidirectional association between psoriasis and inflammatory bowel disease—a systematic review and meta-analysis

F Alinaghi, HG Tekin, J Burisch, JJ Wu… - Journal of Crohn's …, 2020 - academic.oup.com
Abstract Background and Aims Epidemiological studies have established an association
between psoriasis and inflammatory bowel disease [IBD], ie ulcerative colitis [UC] and …

Paradoxical reactions to biologicals for psoriasis

E Camela, L Potestio, G Fabbrocini… - Expert Opinion on …, 2022 - Taylor & Francis
The growing availability of target therapies for psoriasis (biologicals) has dramatically
changed the prognosis of the disease. Currently, the therapeutic goal is represented by a …

Psoriasis as an adverse reaction to biologic agents beyond anti-TNF-α therapy

A Karamanakos, T Vergou, S Panopoulos… - European Journal of …, 2021 - Springer
New onset or exacerbation of pre-existing psoriasis after therapeutic TNF-α inhibition is a
well-described phenomenon. Over the last two decades, similar cases of paradoxical …

Pyoderma gangrenosum treated with secukinumab: A case report

ML McPhie, MG Kirchhof - SAGE Open Medical Case …, 2020 - journals.sagepub.com
Pyoderma gangrenosum is a challenging disease to manage, due in part to the lack of
approved treatment therapies. Recently, the emergence of biologic agents has expanded …

The dark side of the moon: the immune-mediated adverse events of IL-17A/IL-17R inhibition

F Messina, S Piaserico - Journal of Dermatological Treatment, 2022 - Taylor & Francis
As aberrant IL-17 signaling plays a critical role in the pathogenesis of psoriasis, biologic
agents targeting this pathway have become an important weapon against this disease …

Tumor necrosis factors‐α inhibition‐induced paradoxical psoriasis: A case series and literature review

N Lian, L Zhang, M Chen - Dermatologic Therapy, 2020 - Wiley Online Library
Abstract Today, anti‐12/IL23, anti‐IL17, and anti‐IL23 provide more efficacious and/or safer
treatment options for psoriasis. Though, anti‐TNF remains a gold standard in the therapy of …

Drug‐induced psoriasiform alopecia associated with interleukin‐17 inhibitor therapy

TL Tan, L Taglia, P Yazdan - Journal of cutaneous pathology, 2021 - Wiley Online Library
Drug‐induced psoriasiform alopecia is an increasingly recognized form of alopecia mostly
reported in association with TNF‐alpha inhibitors. However, drug‐induced psoriasiform …