Applications of the regenerative capacity of platelets in modern medicine

E Cecerska-Heryć, M Goszka, N Serwin… - Cytokine & growth factor …, 2022 - Elsevier
Platelets produce platelet growth factors such as PDGF, IGF-1, EGF-, HGF, TGFβ, bFGF, and
VEGF, which are crucial in regulating all stages of the wound healing process. The source of …

[HTML][HTML] Recent advances in periodontal regeneration: A biomaterial perspective

Y Liang, X Luan, X Liu - Bioactive materials, 2020 - Elsevier
Periodontal disease (PD) is one of the most common inflammatory oral diseases, affecting
approximately 47% of adults aged 30 years or older in the United States. If not treated …

[HTML][HTML] Nanomaterial-based therapy for wound healing

A Kushwaha, L Goswami, BS Kim - Nanomaterials, 2022 - mdpi.com
Poor wound healing affects millions of people globally, resulting in increased mortality rates
and associated expenses. The three major complications associated with wounds are:(i) the …

A review on nanoparticle based treatment for wound healing

NK Rajendran, SSD Kumar, NN Houreld… - Journal of Drug Delivery …, 2018 - Elsevier
Wound care management relies mainly on the development of new and effective wound
dressing materials, and it continues to be an intense area of research in chronic wound care …

[HTML][HTML] Biomimetic delivery of signals for bone tissue engineering

M Dang, L Saunders, X Niu, Y Fan, PX Ma - Bone research, 2018 - nature.com
Bone tissue engineering is an exciting approach to directly repair bone defects or engineer
bone tissue for transplantation. Biomaterials play a pivotal role in providing a template and …

[HTML][HTML] Treatment of periodontal intrabony defects using autologous periodontal ligament stem cells: a randomized clinical trial

FM Chen, LN Gao, BM Tian, XY Zhang… - Stem cell research & …, 2016 - Springer
Background Periodontitis, which progressively destroys tooth-supporting structures, is one of
the most widespread infectious diseases and the leading cause of tooth loss in adults …

Clinical concepts for regenerative therapy in intrabony defects

P Cortellini, MS Tonetti - Periodontology 2000, 2015 - Wiley Online Library
Evidence indicates that periodontal regeneration is an efficacious and predictable
procedure for the treatment of isolated and multiple intrabony defects. Meta‐analyses from …

The FGF family: biology, pathophysiology and therapy

A Beenken, M Mohammadi - Nature reviews Drug discovery, 2009 - nature.com
The family of fibroblast growth factors (FGFs) regulates a plethora of developmental
processes, including brain patterning, branching morphogenesis and limb development …

Engineering the regenerative microenvironment with biomaterials

JJ Rice, MM Martino, L De Laporte… - Advanced …, 2013 - Wiley Online Library
Modern synthetic biomaterials are being designed to integrate bioactive ligands within
hydrogel scaffolds for cells to respond and assimilate within the matrix. These advanced …

Extracellular matrix-inspired growth factor delivery systems for bone regeneration

MM Martino, PS Briquez, K Maruyama… - Advanced drug delivery …, 2015 - Elsevier
Growth factors are very promising molecules to enhance bone regeneration. However, their
translation to clinical use has been seriously limited, facing issues related to safety and cost …