[HTML][HTML] Therapeutic trials in difficult to treat steroid sensitive nephrotic syndrome: challenges and future directions

AM McKay, RS Parekh, D Noone - Pediatric nephrology, 2023 - Springer
Steroid sensitive nephrotic syndrome is a common condition in pediatric nephrology, and
most children have excellent outcomes. Yet, 50% of children will require steroid-sparing …

[HTML][HTML] Glomerular Diseases Across Lifespan: Key Differences in Diagnostic and Therapeutic Approaches

M Windpessl, B Odler, IM Bajema, D Geetha… - Seminars in …, 2023 - Elsevier
Glomerular diseases are common causes of chronic kidney disease in childhood,
adolescence, and adulthood. The epidemiology of glomerular diseases differs between …

[HTML][HTML] Clinical practice guidelines for nephrotic syndrome: consensus is emerging

A Sinha, A Bagga - Pediatric Nephrology, 2022 - Springer
Nephrotic syndrome is one of the most common chronic kidney diseases (CKD) in children
with an estimated incidence of 2.92 (range 1.15–16.9) per 100,000 children per year [1]. The …

Comprehensive mapping of saliva by multiomics in children with idiopathic nephrotic syndrome

Q Ye, H Liu, H Meng, D Wang, J Zhang, S Zhu… - Nephrology, 2024 - Wiley Online Library
Aim Saliva can reflect an individual's physiological status or susceptibility to systemic
disease. However, little attention has been given to salivary analysis in children with …

[HTML][HTML] Current therapies in nephrotic syndrome: HDAC inhibitors, an emerging therapy for kidney diseases

R Varghese, A Majumdar - Current Research in Biotechnology, 2021 - Elsevier
Nephrotic syndrome (NS) is one amongst the foremost chronic kidney conditions occurring
in children as well as in adults with a characteristic feature of podocyte injury. Currently …

[HTML][HTML] Commentary on “Pediatric Idiopathic Steroid-sensitive Nephrotic Syndrome Diagnosis and Therapy-Short version of the updated German Best Practice …

R Ehren, MR Benz, PT Brinkkötter, J Dötsch… - Pediatric …, 2021 - Springer
Childhood idiopathic nephrotic syndrome is rare but represents the most common
glomerular disease in the pediatric cohort. Glucocorticoid (steroid) treatment depicts the …

Adrenocortical suppression in children with nephrotic syndrome treated with corticosteroids

GM Krishna, A Dabas, M Mantan, A Kumar M… - Pediatric …, 2024 - Springer
Background Children with nephrotic syndrome are exposed to alternate day steroids for
prolonged periods and this poses the need for evaluation of adrenocortical suppression …

The first randomized controlled trial in pediatric nephrology: the history of the International Study of Kidney Disease in Children (ISKDC)

WA Primack, RL Chevalier, A Friedman, KV Lemley… - Pediatric …, 2023 - Springer
Abstract The International Study of Kidney Disease in Children (ISKDC), begun in 1966,
conducted the first international collaborative randomized blinded controlled trial in pediatric …

[HTML][HTML] Early Rituximab as an Add-On Therapy in Children with the Initial Episode of Nephrotic Syndrome

J Liu, F Deng, X Wang, C Liu, S Sun, R Zhang… - Kidney International …, 2024 - Elsevier
Abstracts Introduction The approximately 70% 12-month relapse in children experiencing
the initial episode of steroid-sensitive nephrotic syndrome (SSNS) is a significant concern …

Idiopathic nephrotic syndrome: a clinical approach

K Norman, M Christian - Paediatrics and Child Health, 2022 - Elsevier
Children with new-onset nephrotic syndrome invariably present to general paediatrics in the
first instance. Many with known nephrotic syndrome under the care of a paediatric …