[HTML][HTML] Therapeutic trials in difficult to treat steroid sensitive nephrotic syndrome: challenges and future directions
Steroid sensitive nephrotic syndrome is a common condition in pediatric nephrology, and
most children have excellent outcomes. Yet, 50% of children will require steroid-sparing …
most children have excellent outcomes. Yet, 50% of children will require steroid-sparing …
[HTML][HTML] Glomerular Diseases Across Lifespan: Key Differences in Diagnostic and Therapeutic Approaches
Glomerular diseases are common causes of chronic kidney disease in childhood,
adolescence, and adulthood. The epidemiology of glomerular diseases differs between …
adolescence, and adulthood. The epidemiology of glomerular diseases differs between …
[HTML][HTML] Clinical practice guidelines for nephrotic syndrome: consensus is emerging
Nephrotic syndrome is one of the most common chronic kidney diseases (CKD) in children
with an estimated incidence of 2.92 (range 1.15–16.9) per 100,000 children per year [1]. The …
with an estimated incidence of 2.92 (range 1.15–16.9) per 100,000 children per year [1]. The …
Comprehensive mapping of saliva by multiomics in children with idiopathic nephrotic syndrome
Q Ye, H Liu, H Meng, D Wang, J Zhang, S Zhu… - Nephrology, 2024 - Wiley Online Library
Aim Saliva can reflect an individual's physiological status or susceptibility to systemic
disease. However, little attention has been given to salivary analysis in children with …
disease. However, little attention has been given to salivary analysis in children with …
[HTML][HTML] Current therapies in nephrotic syndrome: HDAC inhibitors, an emerging therapy for kidney diseases
R Varghese, A Majumdar - Current Research in Biotechnology, 2021 - Elsevier
Nephrotic syndrome (NS) is one amongst the foremost chronic kidney conditions occurring
in children as well as in adults with a characteristic feature of podocyte injury. Currently …
in children as well as in adults with a characteristic feature of podocyte injury. Currently …
[HTML][HTML] Commentary on “Pediatric Idiopathic Steroid-sensitive Nephrotic Syndrome Diagnosis and Therapy-Short version of the updated German Best Practice …
R Ehren, MR Benz, PT Brinkkötter, J Dötsch… - Pediatric …, 2021 - Springer
Childhood idiopathic nephrotic syndrome is rare but represents the most common
glomerular disease in the pediatric cohort. Glucocorticoid (steroid) treatment depicts the …
glomerular disease in the pediatric cohort. Glucocorticoid (steroid) treatment depicts the …
Adrenocortical suppression in children with nephrotic syndrome treated with corticosteroids
Background Children with nephrotic syndrome are exposed to alternate day steroids for
prolonged periods and this poses the need for evaluation of adrenocortical suppression …
prolonged periods and this poses the need for evaluation of adrenocortical suppression …
The first randomized controlled trial in pediatric nephrology: the history of the International Study of Kidney Disease in Children (ISKDC)
WA Primack, RL Chevalier, A Friedman, KV Lemley… - Pediatric …, 2023 - Springer
Abstract The International Study of Kidney Disease in Children (ISKDC), begun in 1966,
conducted the first international collaborative randomized blinded controlled trial in pediatric …
conducted the first international collaborative randomized blinded controlled trial in pediatric …
[HTML][HTML] Early Rituximab as an Add-On Therapy in Children with the Initial Episode of Nephrotic Syndrome
J Liu, F Deng, X Wang, C Liu, S Sun, R Zhang… - Kidney International …, 2024 - Elsevier
Abstracts Introduction The approximately 70% 12-month relapse in children experiencing
the initial episode of steroid-sensitive nephrotic syndrome (SSNS) is a significant concern …
the initial episode of steroid-sensitive nephrotic syndrome (SSNS) is a significant concern …
Idiopathic nephrotic syndrome: a clinical approach
K Norman, M Christian - Paediatrics and Child Health, 2022 - Elsevier
Children with new-onset nephrotic syndrome invariably present to general paediatrics in the
first instance. Many with known nephrotic syndrome under the care of a paediatric …
first instance. Many with known nephrotic syndrome under the care of a paediatric …