Recent advances in carbon and nitrogen metabolism in C3 plants
C and N are the most important essential elements constituting organic compounds in
plants. The shoots and roots depend on each other by exchanging C and N through the …
plants. The shoots and roots depend on each other by exchanging C and N through the …
Alternative animal models of aging research
S Holtze, E Gorshkova, S Braude… - Frontiers in Molecular …, 2021 - frontiersin.org
Most research on mechanisms of aging is being conducted in a very limited number of
classical model species, ie, laboratory mouse (Mus musculus), rat (Rattus norvegicus …
classical model species, ie, laboratory mouse (Mus musculus), rat (Rattus norvegicus …
Targeting LC3 and Beclin-1 autophagy genes suppresses proliferation, survival, migration and invasion by inhibition of Cyclin-D1 and uPAR/Integrin β1/Src signaling …
Z Hamurcu, N Delibaşı, S Geçene, EF Şener… - Journal of cancer …, 2018 - Springer
Autophagy is a catabolic process for degrading dysfunctional proteins and organelles, and
closely associated with cancer cell survival under therapeutic, metabolic stress, hypoxia …
closely associated with cancer cell survival under therapeutic, metabolic stress, hypoxia …
[HTML][HTML] Suppression of PI3K signaling is linked to autophagy activation and the spatiotemporal induction of the lens organelle free zone
R Gheyas, R Ortega-Alvarez, D Chauss… - Experimental cell …, 2022 - Elsevier
The terminal steps of lens cell differentiation require elimination of all organelles to create a
central Organelle Free Zone (OFZ) that is required for lens function of focusing images on …
central Organelle Free Zone (OFZ) that is required for lens function of focusing images on …
Redox status regulates autophagy in thymic stromal cells and promotes T cell tolerance
MK Semwal, AK Hester, Y Xiao… - Proceedings of the …, 2022 - National Acad Sciences
Thymic stromal cells (TSCs) are critical regulators of T cell tolerance, but their basic biology
has remained under-characterized because they are relatively rare and difficult to isolate …
has remained under-characterized because they are relatively rare and difficult to isolate …
[HTML][HTML] TGF-β2-induced EMT is dampened by inhibition of autophagy and TNF-α treatment
S Dash, PM Sarashetti, B Rajashekar, R Chowdhury… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) typically develops in a chronic inflammatory setting causal
to release of a plethora of growth factors and cytokines. However, the molecular effect of …
to release of a plethora of growth factors and cytokines. However, the molecular effect of …
[HTML][HTML] Potential ceRNA networks involved in autophagy suppression of pancreatic cancer caused by chloroquine diphosphate: a study based on differentially …
DM Wei, MT Jiang, P Lin, H Yang… - International …, 2019 - spandidos-publications.com
Autophagy has been reported to be involved in the occurrence and development of
pancreatic cancer. However, the mechanism of autophagy‑associated non‑coding RNAs …
pancreatic cancer. However, the mechanism of autophagy‑associated non‑coding RNAs …
Learning of nature: The curious case of the naked mole rat
FA Lagunas-Rangel, V Chávez-Valencia - Mechanisms of Ageing and …, 2017 - Elsevier
Naked mole rats (NMRs) are the longest-living rodents known, living up to approximately 30
years and showing sustained good health. Nowadays, NMRs are considered excellent …
years and showing sustained good health. Nowadays, NMRs are considered excellent …
The use of non-traditional models in the study of cancer resistance—the case of the naked mole rat
A Shepard, JL Kissil - Oncogene, 2020 - nature.com
Non-traditional model organisms are typically defined as any model the deviates from the
typical laboratory animals, such as mouse, rat, and worm. These models are becoming …
typical laboratory animals, such as mouse, rat, and worm. These models are becoming …
Compression stress induces nucleus pulposus cell autophagy by inhibition of the PI3K/AKT/mTOR pathway and activation of the JNK pathway
Z Li, J Wang, X Deng, D Huang, Z Shao… - Connective Tissue …, 2021 - Taylor & Francis
Purpose: Reactive oxygen species (ROS) are related to compression stress-induced
nucleus pulposus (NP) cell autophagy, but the specific mechanism is unknown in …
nucleus pulposus (NP) cell autophagy, but the specific mechanism is unknown in …