Cardiovascular disease, particularly coronary artery dis-ease resulting from accelerated
atherosclerosis, is the leading cause of morbidity and mortality in patients with diabetes …

Objectives: This study was designed to determine whether admission B-type natriuretic
peptide (BNP) levels are predictive of in-hospital mortality in acute decompensated heart …

Coronary heart disease is a major cause of mortality and morbidity worldwide. The
incidence of mechanical complications of acute myocardial infarction (AMI) has gone down …

Background The appropriate treatment for patients in whom reperfusion fails to occur after
thrombolytic therapy for acute myocardial infarction remains unclear. There are few data …

ContextThe benefit of clopidogrel pretreatment before percutaneous coronary intervention
(PCI) remains debated and its use has not been universally adopted. ObjectiveTo determine …

Context Several practice guidelines recommend that depression be evaluated and treated in
patients with cardiovascular disease, but the potential benefits of this are unclear. Objective …

The American College of Cardiology (ACC)/American Heart Association (AHA) Task Force
on Practice Guidelines regularly reviews existing guidelines to determine when an update or …

Background The most effective magnitude and timing of antiplatelet therapy is important in
patients with acute ST-elevation myocardial infarction (STEMI). We investigated whether the …

Importance Clinical decisions are ideally based on evidence generated from multiple
randomized controlled trials (RCTs) evaluating clinical outcomes, but historically, few clinical …

Background Unfractionated heparin is often used as adjunctive therapy with fibrinolysis in
patients with ST-elevation myocardial infarction. We compared a low-molecular-weight …