Non-small cell lung cancer (NSCLC) brain metastases present a significant treatment
challenge due to limited drug delivery efficiency and severe adverse reactions. In this study …

Significant challenges persist in enhancing the delivery efficiency of tumor nanomedicines,
predominantly due to the difficulty of successfully surpassing pathophysiological barriers …

ALK-positive NSCLC patients demonstrate initial responses to ALK tyrosine kinase inhibitor
(TKI) treatments, but eventually develop resistance, causing rapid tumor relapse and poor …

Förster resonance energy transfer (FRET) probes are a promising tool for studying
numerous biochemical processes. In this paper, we show the application of the FRET …

Stabilization against the dilution-dependent disassembly of self-assembled nanoparticles is
a requirement for in vivo application. Herein, we propose a simple and biocompatible cross …

Supramolecular chemistry exploits non-covalent intramolecular interactions to form
structures such as host-guest complexes and crystalline porous materials. Supramolecular …

Biotherapeutic PEGylation to prolong action of medications has gained popularity over the
last decades. Various hydrophilic natural polymers have been developed to tackle the …

Advances in polymer chemistry can provide convenient access to more complex polymeric
architectures, such as miktoarm star polymers. In comparison to their linear counterparts, the …

The clinical translation of polysarcosine (pSar) as polyethylene glycol (PEG) replacement in
the development of novel nanomedicines creates a broad demand of polymeric material in …

Modern nanostructures must fulfill a wide range of functions to be valuable, leading to the
combi-nation of various nano-objects into hierarchical assemblies. Hybrid Nanoparticles …