Drug memory reconsolidation: from molecular mechanisms to the clinical context
AL Milton - Translational Psychiatry, 2023 - nature.com
Since its rediscovery at the beginning of the 21st Century, memory reconsolidation has been
proposed to be a therapeutic target for reducing the impact of emotional memories that can …
proposed to be a therapeutic target for reducing the impact of emotional memories that can …
[HTML][HTML] Favipiravir and its structural analogs: Antiviral activity and synthesis methods
ID Konstantinova, VL Andronova, IV Fateev… - Acta naturae, 2022 - ncbi.nlm.nih.gov
Pyrazine-3-carboxamide-based antiviral compounds have been under intensive study for
the last 20 years. One of these compounds, favipiravir (6-fluoro-3-hydroxypyrazine-2 …
the last 20 years. One of these compounds, favipiravir (6-fluoro-3-hydroxypyrazine-2 …
Chronic administration of a norepinephrine antagonist prevents and partially reverses escalation of cocaine self‐administration
H Beldjoud, A Avelar, G de Guglielmo… - Addiction …, 2023 - Wiley Online Library
Anxiety is a critical component of the development and maintenance of drug addiction;
however, anti‐anxiety medications such as benzodiazepines and beta‐blockers (β …
however, anti‐anxiety medications such as benzodiazepines and beta‐blockers (β …
Stimulant and hallucinogenic novel psychoactive substances; an update
F Schifano, A Vento, N Scherbaum… - Expert Review of …, 2023 - Taylor & Francis
Introduction The renewed interest in considering a range of stimulants, psychedelics and
dissociatives as therapeutics emphasizes the need to draft an updated overview of these …
dissociatives as therapeutics emphasizes the need to draft an updated overview of these …
DNA methyltransferase activity in the basolateral amygdala is critical for reconsolidation of a heroin reward memory
S Qian, C Shi, S Huang, C Yang, Y Luo - Frontiers in Molecular …, 2022 - frontiersin.org
The persistence of drug memory contributes to relapse to drug seeking. The association
between repeated drug exposure and drug-related cues leads to cravings triggered by drug …
between repeated drug exposure and drug-related cues leads to cravings triggered by drug …
The Cdk5 inhibitor β‐butyrolactone impairs reconsolidation of heroin‐associated memory in the rat basolateral amygdala
H Li, H Zhao, T Hu, L Meng, X Mo, M Gong… - Addiction …, 2023 - Wiley Online Library
The persistence of maladaptive heroin‐associated memory, which is triggered by drug‐
related stimuli that remind the individual of the drug's pleasurable and rewarding effects, can …
related stimuli that remind the individual of the drug's pleasurable and rewarding effects, can …
Inhibition of glycogen synthase kinase 3β activity in the basolateral amygdala disrupts reconsolidation and attenuates heroin relapse
Y Xie, Y Zhang, T Hu, Z Zhao, Q Liu… - Frontiers in Molecular …, 2022 - frontiersin.org
Exposure to a heroin-associated conditioned stimulus can reactivate drug reward memory,
trigger drug cravings, and induce relapse in heroin addicts. The amygdala, a brain region …
trigger drug cravings, and induce relapse in heroin addicts. The amygdala, a brain region …
Endogenous opiates and behavior: 2021
RJ Bodnar - Peptides, 2023 - Elsevier
This paper is the forty-fourth consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …
research concerning the endogenous opioid system, summarizing articles published during …
The mechanisms and boundary conditions of drug memory reconsolidation
L Chen, H Yan, Y Wang, Z He, Q Leng… - Frontiers in …, 2021 - frontiersin.org
Drug addiction can be seen as a disorder of maladaptive learning characterized by relapse.
Therefore, disrupting drug-related memories could be an approach to improving therapies …
Therefore, disrupting drug-related memories could be an approach to improving therapies …
[HTML][HTML] Manipulating critical memory periods to treat psychiatry disorders
J Deng, X Lin, Y Zheng, S Su, X Liu, K Yuan, L Shi… - Science Bulletin, 2023 - Elsevier
The persistence of pathological memory is the basis of several psychiatric disorders.
Memory retrieval induces “reconsolidation”, a time interval during which the original memory …
Memory retrieval induces “reconsolidation”, a time interval during which the original memory …