[HTML][HTML] Medical gas plasma augments bladder cancer cell toxicity in preclinical models and patient-derived tumor tissues

N Gelbrich, L Miebach, J Berner, E Freund… - Journal of Advanced …, 2023 - Elsevier
Introduction Medical gas plasma therapy has been successfully applied to several types of
cancer in preclinical models. First palliative tumor patients suffering from advanced head …

Role of FGF-18 in bone regeneration

K Murugaiyan, S Amirthalingam, NSY Hwang… - Journal of Functional …, 2023 - mdpi.com
In tissue engineering, three key components are cells, biological/mechanical cues, and
scaffolds. Biological cues are normally proteins such as growth factors and their derivatives …

[HTML][HTML] Peptide ligands targeting FGF receptors promote recovery from dorsal root crush injury via AKT/mTOR signaling

Y Zhao, Q Wang, C Xie, Y Cai, X Chen, Y Hou, L He… - Theranostics, 2021 - ncbi.nlm.nih.gov
Background: Fibroblast growth factor receptors (FGFRs) are key targets for nerve
regeneration and repair. The therapeutic effect of exogenous recombinant FGFs in vivo is …

Elucidating Fibroblast Growth Factor–Induced Kinome Dynamics Using Targeted Mass Spectrometry and Dynamic Modeling

TS Veth, C Francavilla, AJR Heck, M Altelaar - Molecular & Cellular …, 2023 - ASBMB
Fibroblast growth factors (FGFs) are paracrine or endocrine signaling proteins that, activated
by their ligands, elicit a wide range of health and disease-related processes, such as cell …

[HTML][HTML] Fibroblast growth factor receptor 1-bound extracellular vesicle as novel therapy for osteoarthritis

BG de Liyis, J Nolan, MA Maharjana - Biomedicine, 2022 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is a joint condition that causes significant impairment of the chondrocyte.
The gradual degradation of the cartilage lining of one or more freely moving joints, as well …

Fibroblast growth factor receptor (FGFR) inhibitors in cholangiocarcinoma: current status, insight on resistance mechanisms and toxicity management

S Chakrabarti, HD Finnes, A Mahipal - Expert Opinion on Drug …, 2022 - Taylor & Francis
Introduction Cholangiocarcinoma (CCA) frequently presents with an advanced disease
precluding curative surgery and shows modest response to chemotherapy. Advancements …

[HTML][HTML] Craniofacial sutures: Signaling centres integrating mechanosensation, cell signaling, and cell differentiation

DM Roth, K Souter, D Graf - European Journal of Cell Biology, 2022 - Elsevier
Cranial sutures are dynamic structures in which stem cell biology, bone formation, and
mechanical forces interface, influencing the shape of the skull throughout development and …

Neurodevelopmental disorders, immunity, and cancer are connected

R Nussinov, CJ Tsai, H Jang - Iscience, 2022 - cell.com
Immunity could be viewed as the common factor in neurodevelopmental disorders and
cancer. The immune and nervous systems coevolve as the embryo develops. Immunity can …

AMEND: active module identification using experimental data and network diffusion

SS Boyd, C Slawson, JA Thompson - BMC bioinformatics, 2023 - Springer
Background Molecular interaction networks have become an important tool in providing
context to the results of various omics experiments. For example, by integrating …

Exploring the structural and functional diversity among FGF signals: A comparative study of human, mouse, and xenopus FGF ligands in embryonic development and …

RS Goutam, V Kumar, U Lee, J Kim - International Journal of Molecular …, 2023 - mdpi.com
Fibroblast growth factors (FGFs) encode a large family of growth factor proteins that activate
several intracellular signaling pathways to control diverse physiological functions. The …