Abstract Ischemia-reperfusion (I/R) injury paradoxically occurs during reperfusion following
ischemia, exacerbating the initial tissue damage. The limited understanding of the intricate …

Remote ischemic conditioning (RIC) is the application of brief periods of ischemia to an
organ or tissue with the aim of inducing protection from ischemia in a distant organ. It was …

Current treatments for Parkinson's disease (PD) are primarily symptomatic, leaving a need
for treatments that mitigate disease progression. One emerging neuroprotective strategy is …

Some studies have confirmed the neuroprotective effect of remote ischemic conditioning
against stroke. Although numerous animal researches have shown that the neuroprotective …

Ischemia refers to a reduced supply of oxygen and nutrient to the vital organ of the body.
Reperfusion to the ischemic organ is the only way to salvage injury due to ischemia …

Background Death-associated protein kinase (DAPK1) is one of the positive regulators of
apoptosis, and it is widely involved in apoptosis induced by multiple pathways. We …

The aim of the present study was to observe the effect of Rho‑kinase on remote ischemic
post‑conditioning (RIPostC) and explore the underlying mechanisms. Male Sprague Dawley …

Aneurysmal subarachnoid hemorrhage (SAH) carries significant mortality and morbidity,
with nearly half of SAH survivors having major cognitive dysfunction that impairs their …

The inflammatory response following subarachnoid hemorrhage (SAH) may lead to Early
Brain Injury and subsequently contribute to poor prognosis such as cognitive impairment in …

Background: Preventing delayed cerebral ischemia (DCI) after subarachnoid hemorrhage
(SAH) remains an important therapeutic target. Preconditioning stimulates multiple …