Prevention of acute exacerbations of COPD: American college of chest physicians and Canadian thoracic society guideline

GJ Criner, J Bourbeau, RL Diekemper, DR Ouellette… - Chest, 2015 - Elsevier
BACKGROUND: COPD is a major cause of morbidity and mortality in the United States as
well as throughout the rest of the world. An exacerbation of COPD (periodic escalations of …

Preventing postoperative pulmonary complications: the role of the anesthesiologist

DO Warner, RB Weiskopf - The Journal of the American Society of …, 2000 - pubs.asahq.org
THE Confederate General “Stonewall” Jackson was one of the earliest known victims of a
respiratory complication after surgery, dying of pneumonia 10 days after an otherwise …

Tiotropium (Spiriva™): mechanistical considerations and clinical profile in obstructive lung disease

B Disse, GA Speck, KL Rominger, TJ Witek Jr… - Life sciences, 1999 - Elsevier
Inhaled antimuscarinics, often called anticholinergics in clinical medicine, are established as
first line bronchodilators in COPD. Tiotropium has been developed as a new generation …

Inhaled formoterol dry powder versus ipratropium bromide in chronic obstructive pulmonary disease

R Dahl, LAPM Greefhorst, D Nowak… - American journal of …, 2001 - atsjournals.org
We compared the effectiveness of inhaled formoterol with that of ipratropium in the treatment
of chronic obstructive pulmonary disease (COPD). After a 2-wk run-in period, 780 patients …

Monitoring in chronic disease: a rational approach

P Glasziou, L Irwig, D Mant - Bmj, 2005 - bmj.com
The ritual of routine visits for most chronic diseases usually includes monitoring to check on
the progress or regress of the disease and the development of complications. Such checks …

The role of long-acting bronchodilators in the management of stable COPD

DP Tashkin, CB Cooper - Chest, 2004 - Elsevier
Bronchodilators form the foundation of symptomatic treatment of COPD. Several long-acting
bronchodilators are now available for use in COPD, but publications of large-scale studies of …

A randomised controlled comparison of tiotropium and ipratropium in the treatment of chronic obstructive pulmonary disease

JA Van Noord, TA Bantje, ME Eland, L Korducki… - Thorax, 2000 - thorax.bmj.com
BACKGROUND A study was undertaken to evaluate and compare the efficacy and safety of
tiotropium and ipratropium during long term treatment in patients with stable chronic …

Use of a Long-acting Inhaled β2-Adrenergic Agonist, Salmeterol Xinafoate, in Patients with Chronic Obstructive Pulmonary Disease

SI RENNARD, W ANDERSON… - American journal of …, 2001 - atsjournals.org
Chronic obstructive pulmonary disease (COPD) is a condition in which continuous
bronchodilation may have clinical advantages. This study evaluated salmeterol, a β-agonist …

The role of anticholinergics in chronic obstructive pulmonary disease

PJ Barnes - The American Journal of Medicine Supplements, 2004 - Elsevier
Anticholinergics are the bronchodilators of choice in the management of chronic obstructive
pulmonary disease (COPD). They work by blocking muscarinic receptors in airway smooth …

Preclinical evaluation of long-acting muscarinic antagonists: comparison of tiotropium and investigational drugs

P Casarosa, T Bouyssou, S Germeyer… - … of Pharmacology and …, 2009 - ASPET
Chronic obstructive pulmonary disease (COPD) is characterized by progressive airflow
limitation caused by persistent inflammatory processes in the airways. An increased …