Toxic effects of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) in developing red seabream (Pagrus major) embryo: an association of morphological deformities with …
The toxicity of dioxins such as 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) is mainly
mediated by the aryl hydrocarbon receptor (AHR), which regulates the multiple target genes …
mediated by the aryl hydrocarbon receptor (AHR), which regulates the multiple target genes …
CYP1A in TCDD toxicity and in physiology–with particular reference to CYP dependent arachidonic acid metabolism and other endogenous substrates
AB Rifkind - Drug metabolism reviews, 2006 - Taylor & Francis
Toxicologic and physiologic roles of CYP1A enzyme induction, the major biochemical effect
of aryl hydrocarbon receptor activation by TCDD and other receptor ligands, are unknown …
of aryl hydrocarbon receptor activation by TCDD and other receptor ligands, are unknown …
The role of development and duration of exposure to the embryotoxicity of diazinon
JT Hamm, DE Hinton - Aquatic toxicology, 2000 - Elsevier
Medaka, Oryzias latipes, were used as a laboratory surrogate for species of concern to
define the effects of diazinon exposure on teleost embryogenesis. Medaka embryos were …
define the effects of diazinon exposure on teleost embryogenesis. Medaka embryos were …
Activation of transcription factors activator protein-1 and nuclear factor-κB by 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin
A Puga, SJ Barnes, C Chang, H Zhu… - Biochemical …, 2000 - Elsevier
2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin (TCDD; dioxin), the prototype agonist of the aromatic
hydrocarbon (Ah) receptor, is a potent tumor promoter as well as a complete liver …
hydrocarbon (Ah) receptor, is a potent tumor promoter as well as a complete liver …
Dioxin perturbs, in a dose-and time-dependent fashion, steroid secretion, and induces apoptosis of human luteinized granulosa cells
Abstract Dioxin (2, 3, 7, 8-tetrachlorodibenzo-p-dioxin; TCDD) is the most toxic congener of a
large class of environmental pollutants. Several studies have shown that TCDD exposure …
large class of environmental pollutants. Several studies have shown that TCDD exposure …
Modulation of ovarian follicle maturation and effects on apoptotic cell death in Holtzman rats exposed to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) in utero and …
I Heimler, AL Trewin, CL Chaffin, RG Rawlins… - Reproductive …, 1998 - Elsevier
Recent reports have described the reproduction-modulating and endocrine-disrupting
effects following exposure to toxic substances such as 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin …
effects following exposure to toxic substances such as 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin …
TCDD promotes liver fibrosis through disordering systemic and hepatic iron homeostasis
Abstract 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin (TCDD) is a toxic environmental pollutant
which can cause severe health problems, such as fibrosis. However, the toxic effects and …
which can cause severe health problems, such as fibrosis. However, the toxic effects and …
Developmental exposure to a complex PAH mixture causes persistent behavioral effects in naive Fundulus heteroclitus (killifish) but not in a population of PAH …
DR Brown, JM Bailey, AN Oliveri, ED Levin… - Neurotoxicology and …, 2016 - Elsevier
Acute exposures to some individual polycyclic aromatic hydrocarbons (PAHs) and complex
PAH mixtures are known to cause cardiac malformations and edema in the developing fish …
PAH mixtures are known to cause cardiac malformations and edema in the developing fish …
Cardiovascular gene expression profiles of dioxin exposure in zebrafish embryos
HM Handley-Goldstone, MW Grow… - Toxicological …, 2005 - academic.oup.com
Abstract 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin (TCDD) is a widespread environmental
contaminant that causes altered heart morphology, circulatory impairment, edema …
contaminant that causes altered heart morphology, circulatory impairment, edema …
Resolving mechanisms of toxicity while pursuing ecotoxicological relevance?
DE Hinton, SW Kullman, RC Hardman, DC Volz… - Marine Pollution …, 2005 - Elsevier
In this age of modern biology, aquatic toxicological research has pursued mechanisms of
action of toxicants. This has provided potential tools for ecotoxicologic investigations …
action of toxicants. This has provided potential tools for ecotoxicologic investigations …