Lung cancer mortality represents the leading cause of cancer related deaths in the United
States and worldwide. Almost half of these deaths occur in female patients, making lung …

Simple Summary In this review, we present current knowledge of sex hormones in the
process of development of malignant diseases. The impact of sex hormones on immune …

Background Immunotherapy has revolutionized cancer treatment, but most patients are
refractory to immunotherapy or acquire resistance, with the underlying mechanisms …

The use of magnetic nanoparticles (MNPs) in biomedical applications has been wildly opted
due to their unique properties. Here, we designed MNPs loaded with erlotinib (ERL/SPION …

Lung cancer incidence and mortality have significantly increased in women worldwide. Lung
adenocarcinoma is the most common form of lung cancer globally. This type of lung cancer …

DYRK1A is considered a potential cancer therapeutic target, but the role of DYRK1A in
NSCLC oncogenesis and treatment requires further investigation. In our study, high …

Simple Summary Exogenous and endogenous estrogens and associated receptors
modulate signaling pathways with biochemical events implicated in non-small cell lung …

Estrogen promotes non‑small cell lung cancer (NSCLC) metastasis via estrogen receptor β
(ERβ)‑mediated invasiveness‑associated matrix metalloprotease 2 (MMP2) upregulation …

Background Lung cancer death remains the highest among all malignancies. Gender
differences show women have an increased cancer incidence while men have worse …

High ERβ/HER oncogenic signaling defines lung tumors with an aggressive biology. We
previously showed that combining the anti-estrogen fulvestrant with the pan-HER inhibitor …