Systematic omics analysis identifies CCR6 as a therapeutic target to overcome cancer resistance to EGFR inhibitors
Epidermal growth factor receptor inhibitors (EGFRi) have exhibited promising clinical
outcomes in the treatment of various cancers. However, their widespread application has …
outcomes in the treatment of various cancers. However, their widespread application has …
Sex steroid metabolism and actions in non-small cell lung carcinoma
T Asavasupreechar, MSM Chan, R Saito, Y Miki… - The Journal of Steroid …, 2019 - Elsevier
Despite recent development in targeted therapies, lung cancer still remains the leading
cause of cancer death. Therefore, a better understanding of its pathogenesis and …
cause of cancer death. Therefore, a better understanding of its pathogenesis and …
Complex differential diagnosis between primary breast cancer and breast metastasis from EGFR-mutated lung adenocarcinoma: case report and literature review
C Valenza, FM Porta, A Rappa, E Guerini-Rocco… - Current …, 2021 - mdpi.com
We present a case of a woman with epidermal growth factor receptor (EGFR)-mutated lung
adenocarcinoma who received gefitinib for 2 years and obtained a partial response. The …
adenocarcinoma who received gefitinib for 2 years and obtained a partial response. The …
[HTML][HTML] Role of GPER1 in the Mechanism of EGFR-TKIs Resistance in Lung Adenocarcinoma
Z Li, Y Pan, Q Liu, J Wang, C Liu, L Qu, D Li - Frontiers in Oncology, 2022 - frontiersin.org
Epidermal growth factor receptor (EGFR)–tyrosine kinase inhibitors (TKIs) have a good
clinical efficacy in lung adenocarcinoma harboring activating-mutation EGFR. Such EGFR …
clinical efficacy in lung adenocarcinoma harboring activating-mutation EGFR. Such EGFR …
Autocrine 17-β-Estradiol/Estrogen Receptor-α Loop Determines the Response to Immune Checkpoint Inhibitors in Non–Small Cell Lung Cancer
DP Anobile, IC Salaroglio, F Tabbò, S La Vecchia… - Clinical Cancer …, 2023 - AACR
Purpose: The response to immune checkpoint inhibitors (ICI) often differs between genders
in non–small cell lung cancer (NSCLC), but metanalyses results are controversial, and no …
in non–small cell lung cancer (NSCLC), but metanalyses results are controversial, and no …
[PDF][PDF] Dual Effect of Immune Cells within Tumour Microenvironment: Pro-and Anti-Tumour Effects and Their Triggers. Cancers 2022, 14, 1681
AC Peña-Romero, E Orenes-Piñero - 2022 - mdpi.com
Our body is constantly exposed to pathogens or external threats, but with the immune
response that our body can develop, we can fight off and defeat possible attacks or …
response that our body can develop, we can fight off and defeat possible attacks or …
The estrogen pathway as a modulator of response to immunotherapy
MA Velez, TF Burns, LP Stabile - Immunotherapy, 2019 - Future Medicine
Lung cancer is the leading cause of cancer deaths worldwide, with a 5-year survival rate of
about 18%. Thus, there is a great need for novel therapeutic approaches to treat non-small …
about 18%. Thus, there is a great need for novel therapeutic approaches to treat non-small …
EGFR 靶向治疗的现状机遇和挑战
高琳, 虞永峰, 陆舜 - 中国肿瘤临床, 2021 - cjco.cn
肺癌是癌症相关死亡的主要原因. 目前, 肺癌的发病率正在下降, 但患者的生存率仍然较低.
肺癌中超过85% 是非小细胞肺癌(non-small cell lung cancer, NSCLC), 超过60% 的NSCLC …
肺癌中超过85% 是非小细胞肺癌(non-small cell lung cancer, NSCLC), 超过60% 的NSCLC …
Epidemiology and clinicopathological features of lung cancer in patients with prior history of breast cancer
Breast cancer is the most common malignancy in women, and lung cancer, the leading
cause of cancer-related mortality in the United States, is the most common subsequent …
cause of cancer-related mortality in the United States, is the most common subsequent …
Development of a prognostic model for lung adenocarcinoma polarity‐related genes and analysis of immune landscape
H Xu, W Du, X Jing, J Xie, P Li - Biotechnology and Applied …, 2024 - Wiley Online Library
Despite the progress made in the management of lung adenocarcinoma (LUAD), the overall
prognosis for LUAD individuals remains suboptimal. While the role of cell polarity in tumor …
prognosis for LUAD individuals remains suboptimal. While the role of cell polarity in tumor …