Cypermethrin induces apoptosis, autophagy and inflammation via ERS-ROS-NF-κB axis in hepatocytes of carp (Cyprinus carpio)

D Li, K Zhang, C Xu, Y Jiang, J Shan, Z Zhang… - Pesticide Biochemistry …, 2023 - Elsevier
Abstract Cypermethrin (CYP, IUPAC name:[cyano-(3-phenoxyphenyl) methyl] 3-(2, 2-
dichloroethenyl)-2, 2-dimethylcyclopropane-1-carboxylate) is a pyrethroid insecticide that …

Microglia-derived IL-1β promoted neuronal apoptosis through ER stress-mediated signaling pathway PERK/eIF2α/ATF4/CHOP upon arsenic exposure

X Liu, Y Chen, H Wang, Y Wei, Y Yuan, Q Zhou… - Journal of Hazardous …, 2021 - Elsevier
Arsenic is the leading toxicant of hazardous environmental chemicals, which is linked with
neurotoxicity including cognitive dysfunction, neurodevelopmental alterations and …

Resveratrol improves emamectin benzoate-induced pyroptosis and inflammation of Ctenopharyngodon idellus hepatic cells by alleviating oxidative stress …

Y Bi, X Li, H Wei, S Xu - Fish & Shellfish Immunology, 2023 - Elsevier
Emamectin benzoate (EMB) is the most widely used pesticide in the world and contributes to
water pollution. Owing to the lack of a specific antidote, EMB has a severe negative impact …

The NLRP3 inflammasome contributes to inflammation‐induced morphological and metabolic alterations in skeletal muscle

M Eggelbusch, A Shi, BC Broeksma… - Journal of Cachexia …, 2022 - Wiley Online Library
Background Systemic inflammation is associated with skeletal muscle atrophy and
metabolic dysfunction. Although the nucleotide‐binding oligomerization domain‐like …

Advantages and drawbacks of dexamethasone in glioblastoma multiforme

AR Afshari, M Sanati, S Aminyavari, F Shakeri… - Critical Reviews in …, 2022 - Elsevier
The most widespread, malignant, and deadliest type of glial tumor is glioblastoma
multiforme (GBM). Despite radiation, chemotherapy, and radical surgery, the median …

A review: Pharmacology and pharmacokinetics of Schisandrin A

K Fu, H Zhou, C Wang, L Gong, C Ma… - Phytotherapy …, 2022 - Wiley Online Library
Schisandrin A (SA) is a bioactive lignan isolated from the traditional Chinese medicine
Fructus schisandrae chinensis. In recent years, it has attracted extensive attention because …

[HTML][HTML] Mitochondrial mutations and genetic factors determining NAFLD risk

SA Dabravolski, EE Bezsonov, MS Baig… - International journal of …, 2021 - mdpi.com
NAFLD (non-alcoholic fatty liver disease) is a widespread liver disease that is often linked
with other life-threatening ailments (metabolic syndrome, insulin resistance, diabetes …

[HTML][HTML] Ursolic Acid alleviates Neuroinflammation after Intracerebral Hemorrhage by Mediating Microglial pyroptosis via the NF-κB/NLRP3/GSDMD pathway

P Lei, Z Li, Q Hua, P Song, L Gao, L Zhou… - International Journal of …, 2023 - mdpi.com
The neuroinflammatory response after intracerebral hemorrhage (ICH) causes a large
amount of neuronal loss, and inhibiting the inflammatory response can improve the …

Pattern recognition receptor‐mediated inflammation in diabetic vascular complications

X Wang, V Antony, Y Wang, G Wu… - Medicinal Research …, 2020 - Wiley Online Library
The innate immune system contains multiple classes of pattern recognition receptors
(PRRs), which recognize pathogen‐associated molecular patterns (PAMPs) and danger …

[HTML][HTML] Malvidin alleviates mitochondrial dysfunction and ROS accumulation through activating AMPK-α/UCP2 axis, thereby resisting inflammation and apoptosis in …

P Zhao, X Li, Q Yang, Y Lu, G Wang, H Yang… - Frontiers in …, 2023 - frontiersin.org
This study aimed to explore the protective roles of malvidin in life-threatened sepsis-
associated encephalopathy (SAE) and illustrate the underlying mechanism. SAE mice …