2022 update on prostate cancer epidemiology and risk factors—a systematic review

O Bergengren, KR Pekala, K Matsoukas, J Fainberg… - European urology, 2023 - Elsevier
Abstract Context Prostate cancer (PCa) is one of the most common cancers worldwide.
Understanding the epidemiology and risk factors of the disease is paramount to improve …

PIONEER big data platform for prostate cancer: lessons for advancing future real-world evidence research

A Lawlor, K Beyer, B Russell, C Steinbeisser… - Nature Reviews …, 2024 - nature.com
Abstract Prostate Cancer Diagnosis and Treatment Enhancement through the Power of Big
Data in Europe (PIONEER) is a European network of excellence for big data in prostate …

WSB1 Involvement in Prostate Cancer Progression

L Boldrini, M Bardi - Genes, 2023 - mdpi.com
Prostate cancer (PC) is polygenic disease involving many genes, and more importantly a
host of gene–gene interactions, including transcriptional factors. The WSB1 gene is a …

Preliminary effects of risk-adapted PSA screening for prostate cancer after integrating PRS-specific and age-specific variation

X Liu, H Duan, S Liu, Y Zhang, Y Ji, Y Zhang… - Frontiers in …, 2024 - frontiersin.org
Background Although the risk of prostate cancer (PCa) varies across different ages and
genetic risks, it's unclear about the effects of genetic-specific and age-specific prostate …

Transferability and accuracy of electronic health record-based predictors compared to polygenic scores

KE Detrois, T Hartonen, M Teder-Laving, B Jermy… - medRxiv, 2024 - medrxiv.org
Electronic health record (EHR)-based phenotype risk scores (PheRS) leverage individuals'
health trajectories to infer disease risk. Similarly, polygenic scores (PGS) use genetic …

Predictive value of polygenic risk score for prostate cancer incidence and prognosis in the Han Chinese

SC Hung, LW Chang, TH Hsiao, CY Wei, SS Wang… - Scientific Reports, 2024 - nature.com
Although prostate cancer is a common occurrence among males, the relationship between
existing risk prediction models remains unclear. The objective of this hospital-based …

Genetic Susceptibility to Prostate Cancer

T Simic, M Matic, D Jerotic - Prostate Cancer: Advancements in the …, 2024 - Springer
Prostate cancer (PCa) is the second most diagnosed cancer type globally and is one of the
leading causes of death in men. Genetic susceptibility plays a significant role in PCa …

Re: Early Prostate Cancer Deaths Among Men with Higher vs Lower Genetic Risk

SV Carlsson, H Lilja, AJ Vickers… - European …, 2024 - pubmed.ncbi.nlm.nih.gov
Re: Early Prostate Cancer Deaths Among Men with Higher vs Lower Genetic Risk Re: Early
Prostate Cancer Deaths Among Men with Higher vs Lower Genetic Risk Eur Urol. 2024 Sep …

[HTML][HTML] How Well Do Polygenic Risk Scores Identify Men at High Risk for Prostate Cancer? Systematic Review and Meta-Analysis-Beyond the Abstract

A Siltari, A Bjatell, A Auvinen - urotoday.com
Prostate cancer (PCa) has an extremely variable clinical course and especially indolent, low-
risk cases have posed a major problem of overdiagnosis and overtreatment for PSA-based …