Recent CPP-based applications in medicine

K Kurrikoff, Ü Langel - Expert opinion on drug delivery, 2019 - Taylor & Francis
Introduction: Cell-penetrating peptides (CPP) offer versatile tools for the field of drug delivery
and development of macromolecular therapeutics. These tools have matured into …

[图书][B] CPP, cell-penetrating peptides

Ü Langel - 2019 - Springer
The genesis of cell-penetrating peptide research (CPP; also known as prote/peptide
transduction domains, PTD, or Trojan peptides) was born from the publication of two parallel …

[HTML][HTML] Prediction of cell-penetrating potential of modified peptides containing natural and chemically modified residues

V Kumar, P Agrawal, R Kumar, S Bhalla… - Frontiers in …, 2018 - frontiersin.org
Designing drug delivery vehicles using cell-penetrating peptides is a hot area of research in
the field of medicine. In the past, number of in silico methods have been developed for …

Gene silencing via PDA/ERK2‐siRNA‐mediated electrospun fibers for peritendinous antiadhesion

S Liu, F Wu, S Gu, T Wu, S Chen, S Chen… - Advanced …, 2019 - Wiley Online Library
Sustained delivery of small interfering RNA (siRNA) is a challenge in gene silencing for
managing gene‐related disorders. Although nanoparticle‐mediated electrospun fibers …

Mitochondrial-targeted penetrating peptide delivery for cancer therapy

J Wu, J Li, H Wang, CB Liu - Expert Opinion on Drug Delivery, 2018 - Taylor & Francis
Introduction: Mitochondria are promising targeting organelles for anticancer strategies;
however, mitochondria are difficult for antineoplastic drugs to recognize and bind …

[HTML][HTML] Effective in vivo topical delivery of siRNA and gene silencing in intact corneal epithelium using a modified cell-penetrating peptide

D Schiroli, MJ Gómara, E Maurizi, SD Atkinson… - … Therapy-Nucleic Acids, 2019 - cell.com
Autosomal dominantly inherited genetic disorders such as corneal dystrophies are
amenable to allele-specific gene silencing with small interfering RNA (siRNA). siRNA …

A vaccination with boosted cross presentation by ER‐targeted antigen delivery for anti‐tumor immunotherapy

Y Shi, C Zhu, Y Liu, Y Lu, X Li, B Qin… - Advanced …, 2021 - Wiley Online Library
Vaccination is a widely‐accepted resort against the invasion or proliferation of bacteria,
parasites, viruses, and even cancer, which accounts heavily on an active involvement of …

[HTML][HTML] Polymer-based constructs for flexor tendon repair: a review

J Brebels, A Mignon - Polymers, 2022 - mdpi.com
A flexor tendon injury is acquired fast and is common for athletes, construction workers, and
military personnel among others, treated in the emergency department. However, the …

[HTML][HTML] Application of cell penetrating peptides as a Promising drug carrier to combat viral infections

N Khairkhah, A Namvar, A Bolhassani - Molecular Biotechnology, 2023 - Springer
Novel effective drugs or therapeutic vaccines have been already developed to eradicate
viral infections. Some non-viral carriers have been used for effective drug delivery to a target …

Membrane interactions and cell selectivity of amphiphilic anticancer peptides

L Nyström, M Malmsten - Current opinion in colloid & interface science, 2018 - Elsevier
Following considerable research efforts on antimicrobial effects by cationic and amphiphilic
peptides during the last couple of decades, increasing focus has recently been placed on …