Osteosarcoma
HC Beird, SS Bielack, AM Flanagan, J Gill… - Nature reviews Disease …, 2022 - nature.com
Osteosarcoma is the most common primary malignant tumour of the bone. Osteosarcoma
incidence is bimodal, peaking at 18 and 60 years of age, and is slightly more common in …
incidence is bimodal, peaking at 18 and 60 years of age, and is slightly more common in …
Advancing therapy for osteosarcoma
J Gill, R Gorlick - Nature reviews Clinical oncology, 2021 - nature.com
Improving the survival of patients with osteosarcoma has long proved challenging, although
the treatment of this disease is on the precipice of advancement. The increasing feasibility of …
the treatment of this disease is on the precipice of advancement. The increasing feasibility of …
[HTML][HTML] Osteosarcoma: a review of current and future therapeutic approaches
X Zhao, Q Wu, X Gong, J Liu, Y Ma - Biomedical engineering online, 2021 - Springer
Osteosarcoma (OS) is the most common primary bone malignancy that affects children and
young adults. OS is characterized by a high degree of malignancy, strong invasiveness …
young adults. OS is characterized by a high degree of malignancy, strong invasiveness …
[HTML][HTML] Crosstalk between circRNAs and the PI3K/AKT signaling pathway in cancer progression
C Xue, G Li, J Lu, L Li - Signal transduction and targeted therapy, 2021 - nature.com
Circular RNAs (circRNAs), covalently closed noncoding RNAs, are widely expressed in
eukaryotes and viruses. They can function by regulating target gene expression, linear RNA …
eukaryotes and viruses. They can function by regulating target gene expression, linear RNA …
Current and future therapeutic approaches for osteosarcoma
DJ Harrison, DS Geller, JD Gill, VO Lewis… - Expert review of …, 2018 - Taylor & Francis
Introduction: Current treatment of osteosarcoma includes surgical resection of all gross
disease in conjunction with systemic chemotherapy to control micro-metastatic disease. This …
disease in conjunction with systemic chemotherapy to control micro-metastatic disease. This …
[HTML][HTML] Osteosarcoma and metastasis
Osteosarcoma is the most common primary bone malignancy in adolescents. Its high
propensity to metastasize is the leading cause for treatment failure and poor prognosis …
propensity to metastasize is the leading cause for treatment failure and poor prognosis …
Update on osteosarcoma
Abstract Purpose of Review Osteosarcoma (OSA) is the most common primary tumor of
bone, mainly affecting children and adolescents. Here we discuss recent advances in …
bone, mainly affecting children and adolescents. Here we discuss recent advances in …
[HTML][HTML] Targeting molecular mechanisms underlying treatment efficacy and resistance in osteosarcoma: a review of current and future strategies
I Lilienthal, N Herold - International journal of molecular sciences, 2020 - mdpi.com
Osteosarcoma is the most common primary malignant bone tumour in children and
adolescents. Due to micrometastatic spread, radical surgery alone rarely results in cure …
adolescents. Due to micrometastatic spread, radical surgery alone rarely results in cure …
[HTML][HTML] TRIM22 inhibits osteosarcoma progression through destabilizing NRF2 and thus activation of ROS/AMPK/mTOR/autophagy signaling
W Liu, Y Zhao, G Wang, S Feng, X Ge, W Ye, Z Wang… - Redox Biology, 2022 - Elsevier
Osteosarcoma (OS) is a malignant bone tumor that mainly occurs in adolescents. It is
accompanied by a high rate of lung metastasis, and high mortality. Recent studies have …
accompanied by a high rate of lung metastasis, and high mortality. Recent studies have …
A unified therapeutic–prophylactic tissue‐engineering scaffold demonstrated to prevent tumor recurrence and overcoming infection toward bone remodeling
Y Huang, X Zhai, T Ma, M Zhang, H Yang… - Advanced …, 2023 - Wiley Online Library
Osteosarcoma occurs in children and adolescents frequently and leads to a high fatality rate.
Although surgical resection is the most common methods in clinic, patients always suffer …
Although surgical resection is the most common methods in clinic, patients always suffer …