The African eye worm: current understanding of the epidemiology, clinical disease, and treatment of loiasis

M Ramharter, J Butler, G Mombo-Ngoma… - The Lancet Infectious …, 2024 - thelancet.com
Loa loa, the African eye worm, is a filarial pathogen transmitted by blood-sucking flies of the
genus Chrysops. Loiasis primarily affects rural populations residing in the forest and …

Distinct loiasis infection states and associated clinical and hematological manifestations in patients from Gabon

L Veletzky, KA Eberhardt, J Hergeth… - PLOS Neglected …, 2022 - journals.plos.org
Background Loiasis–a filarial disease endemic in Central and West Africa–is increasingly
recognized as significant individual and public health concern. While the understanding of …

Analysis of diagnostic test outcomes in a large loiasis cohort from an endemic region: Serological tests are often false negative in hyper-microfilaremic infections

L Veletzky, KA Eberhardt, J Hergeth… - PLOS Neglected …, 2024 - journals.plos.org
Background The parasitic disease loiasis is associated with significant morbidity and
mortality. Individuals with hyper-microfilaremia (greater than 20,000 microfilariae per mL of …

Low diagnostic performance of thick blood smears of 50 µl in comparison with direct examination of 10 µl blood and the leukoconcentration technique of 5ml blood …

NP M'Bondoukwé, M Owono-Medang… - Parasites & …, 2024 - Springer
Background The aim of this study was to determine performance indicators of thick blood
smears of 50 µl (TBS-50), following the Standards for the Reporting of Diagnostic Accuracy …

Diagnostic performance of capillary and venous blood samples in the detection of Loa loa and Mansonella perstans microfilaraemia using light microscopy

J Mischlinger, RZ Manego… - PLoS Neglected …, 2021 - journals.plos.org
Background Loa loa and Mansonella perstans–the causative agents of loiasis and
mansonellosis—are vector-borne filarial parasites co-endemic in sub-Saharan Africa …

Clinical and epidemiological features of imported loiasis in Beijing: a report from patients returned from Africa

X Li, M Huang, K Bi, Y Zou, F Wang, X Zheng… - BMC Infectious …, 2024 - Springer
Background Loiasis is one of the significant filarial diseases for people living in West and
Central Africa with wide endemic area but is not seen in China. As economy booms and …

Evaluation of knowledge, attitude and practice towards loiasis in the rural community of Sindara, in central African Gabon

TR Hildebrandt, SD Davi, AL Kabwende… - PLOS Neglected …, 2024 - journals.plos.org
Background More than 20 million people are infected with L. loa, and around 40 million live
in high or intermediate-risk areas in West-and Central Africa. Although loiasis is associated …

Prevalence of Loa loa and Mansonella perstans detection in urban areas of Southeast Gabon

EAE Rush, R Dieki, MO Ngounga… - … of Parasitology and …, 2020 - academicjournals.org
Loa loa and Mansonella perstans are two filarial species commonly found in Gabon loiasis
has gained attention because of severe adverse events occurring in individuals harboring …

Imported Loiasis at a Clinical Reference Center in Germany: A Retrospective Case Series

T Nordmann, J Ruge, D Tappe… - The American journal …, 2024 - pubmed.ncbi.nlm.nih.gov
Loiasis is a rarely imported infectious disease that is often difficult to diagnose and treat.
Here we describe clinical features and treatment outcomes of 11 patients with imported …

Recurring Transient Tooth Pain as Newly Described Symptom of Migratory Loiasis: A Mixed-Methods Study in Rural Gabon

TR Hildebrandt, H Ramharter… - … journal of tropical …, 2024 - pubmed.ncbi.nlm.nih.gov
Loiasis, a filarial pathogen exclusively endemic in central and western Africa, causes a wide
spectrum of symptoms. Understanding the breadth of its clinical manifestations is of …