Increased IL-12 inhibits B cells' differentiation to germinal center cells and promotes differentiation to short-lived plasmablasts
SJ Kim, M Caton, C Wang, M Khalil, ZJ Zhou… - The Journal of …, 2008 - rupress.org
B cells activated by antigen in T cell–dependent immune responses can become short-lived
plasma cells, which remain in the spleen, or germinal center–derived memory or plasma …
plasma cells, which remain in the spleen, or germinal center–derived memory or plasma …
Polypyrimidine tract-binding protein is critical for the turnover and subcellular distribution of CD40 ligand mRNA in CD4+ T cells
R Matus-Nicodemos, S Vavassori… - The Journal of …, 2011 - journals.aai.org
Abstract CD40L (CD154) is regulated at the posttranscriptional level by an activation-
induced process that results in a highly stable transcript at extended times of T cell …
induced process that results in a highly stable transcript at extended times of T cell …
Toll-like receptor 3 ligand and retinoic acid enhance germinal center formation and increase the tetanus toxoid vaccine response
Y Ma, AC Ross - Clinical and Vaccine Immunology, 2009 - Am Soc Microbiol
Immunizations with T-cell-dependent antigens induce the formation of germinal centers
(GC), unique lymphoid microenvironments in which antigen-activated B cells undergo class …
(GC), unique lymphoid microenvironments in which antigen-activated B cells undergo class …
Antibody response to canine adenovirus-2 virus vaccination in healthy adult dogs
M Bergmann, M Freisl, Y Zablotski, S Speck, U Truyen… - Viruses, 2020 - mdpi.com
Background: Re-vaccination against canine adenovirus (CAV) is performed in≤ 3-year-
intervals but its necessity is unknown. The study determined anti-CAV antibodies within 28 …
intervals but its necessity is unknown. The study determined anti-CAV antibodies within 28 …
Memory B cells form in aged mice despite impaired affinity maturation and germinal center kinetics
We examined whether age alters the emergence of high-affinity germinal center B (GCB)
cells and switched memory B cells (swB mem) during a primary immune response to a …
cells and switched memory B cells (swB mem) during a primary immune response to a …
Humanized immunoglobulin mice: models for HIV vaccine testing and studying the broadly neutralizing antibody problem
L Verkoczy - Advances in immunology, 2017 - Elsevier
A vaccine that can effectively prevent HIV-1 transmission remains paramount to ending the
HIV pandemic, but to do so, will likely need to induce broadly neutralizing antibody (bnAb) …
HIV pandemic, but to do so, will likely need to induce broadly neutralizing antibody (bnAb) …
Lack of Galectin-3 Disturbs Mesenteric Lymph Node Homeostasis and B Cell Niches in the Course of Schistosoma mansoni Infection
FL Oliveira, C Brand, AA Paula, KD Arcanjo, DK Hsu… - PLoS …, 2011 - journals.plos.org
Galectin-3 is a β-galactoside-binding protein that has been shown to regulate
pathophysiological processes, including cellular activation, differentiation and apoptosis …
pathophysiological processes, including cellular activation, differentiation and apoptosis …
Origins of antinuclear antibodies
WH Reeves, Y Xu, H Zhuang, Y Li, L Yang - Systemic lupus erythematosus, 2011 - Elsevier
Publisher Summary The production of antinuclear antibodies (ANAs) is one of the defining
features of systemic lupus erythematosus (SLE). This chapter reviews what has been …
features of systemic lupus erythematosus (SLE). This chapter reviews what has been …
Aborted germinal center reactions and B cell memory by follicular T cells specific for a B cell receptor V region peptide
RA Heiser, CM Snyder, J St Clair… - The Journal of …, 2011 - journals.aai.org
A fundamental problem in immunoregulation is how CD4+ T cells react to immunogenic
peptides derived from the V region of the BCR that are created by somatic mechanisms …
peptides derived from the V region of the BCR that are created by somatic mechanisms …
Novel nicotine DNA vaccines
(21) Appl. No.: 14/209,845 i and at least one Erin moiety, wherein the at least (22) Filed: Mar
13, 2014 one targeting moiety is linked to the DNA-nanostructure; and Related US …
13, 2014 one targeting moiety is linked to the DNA-nanostructure; and Related US …